The Economist’s Post

#HighlyCitedPapers   📝 A Novel 2-Hit Zebrafish Model to Study Early Pathogenesis of Non-Alcoholic Fatty Liver Disease — Kulkarni, et al.   In this paper, the authors aimed to present a novel 2-hit zebrafish model to replicate aspects of #NAFLD pathogenesis.   Full text is available 👇 https://lnkd.in/d7aqzugb   #medicine #health #research #science

📢 Revolutionary Tech Tackles Soaring Healthcare Costs! 📅 May 20, 2024: The escalating cost of healthcare due to degenerative and metabolic diseases is a concern. 💡 New Quantitative Trait Loci QTL technology combined with complex systems science shows promise in addressing the root causes and developing effective treatments. 🏥 Western lifestyles contribute to disease in complex ways, impacting biological function and systems. 🔬 QTL technology can help unravel the complexity and find potential solutions to healthcare challenges. 🔀 Genetic mutations and damage can affect bodily function, requiring a diverse approach to treatment. ⏰ As diseases progress, they become harder to treat, making it crucial to reduce lifestyle-related damage. 🔬 Understanding the interaction between complex systems and the environment is vital for finding solutions. 👥 The use of breeding, screening, and genomic analysis, along with QTL technology, can unlock biological complexity and address healthcare challenges. #BioprocessUpdates #HealthcareCosts #NewTechnologies #QuantitativeTraitLoci #ComplexSystemsScience #WesternLifestyles #GeneticMutations #EffectiveTreatments #ReduceDamage #ComplexSystems #EnvironmentInteraction #Breeding #GenomicAnalysis #BiologicalComplexity #HealthcareChallenges ▷ Read the full article here: 📎 https://lnkd.in/dGfgxAQZ

🚨 New research sheds light on the gut-brain connection in Parkinson’s treatment! A study led by Dr. Fatima Pereira and a team of international researchers from the University of Southampton, Vienna, Boston, and Aalborg has uncovered how the commonly prescribed Parkinson’s drug entacapone disrupts the gut microbiome. The research, published in Nature Microbiology, reveals that entacapone starves beneficial gut microbes of iron, potentially leading to health complications. 👉 Read the full article and discover how this research could inform better therapies for the millions living with Parkinson’s disease: https://lnkd.in/eUtKP_fG #ParkinsonsDisease #GutMicrobiome #MedicalResearch #Innovation

A little PREVENT update: The study is in full speed, and hundreds of samples are now in the lab being sequenced! At Alba Health, we use deep shotgun metagenomics sequencing technology to analyze extracted DNA from the baby stool samples. This method provides comprehensive microbiome profiling and enables characterization of the microbiome composition. It is the most advanced technology used in microbiome research today, offering insights into both composition and functionality with the highest output. One step further to mapping the connection between the gut microbiome and lifestyle, wellbeing and health during the first year of life! 🎯

The gut microbiome plays a pivotal role in maintaining human health, influencing everything from digestion and metabolism to immune function and even mental health. An imbalance in this complex microbial ecosystem has been linked to a wide range of conditions, including inflammatory bowel disease, obesity, diabetes, and neurological disorders. As a result, understanding the gut microbiome has become crucial for advancing personalized medicine, nutrition, and therapeutic strategies. Next-Generation Sequencing (NGS) technologies, particularly 16s rRNA sequencing, have revolutionized microbiome research by enabling in-depth analysis of microbial communities with unmatched speed and precision. These NGS-based methods allow researchers to explore the diversity and function of gut microorganisms, providing insights that were previously unattainable. We are happy to announce our upcoming workshop on Metagenomics Data Analysis which will deep dive into these cutting-edge NGS techniques. By learning how to process and analyze 16s rRNA sequencing data, participants will gain the skills needed to advance research and clinical applications in this rapidly evolving field. Whether you're working in healthcare, academia, or biotechnology, mastering these techniques is essential for anyone looking to contribute to the future of microbiome science. Register here: https://lnkd.in/dtNR9ghb #Metagenomics #GutMicrobiome #Bioinformatics #HumanHealth

"Nutrition" can be like magic, illustrated by this paper in Ped Res showing that colostrum (nasal instillation) is a strong stimulator of neurogenic growth of nerve tissue, in a murine model. Great basic science, looking fw to see if/how this can be translated in clinical research! #UENPS https://lnkd.in/dMfRPXBH

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies specific to self-molecules in the nucleus, cytoplasm, and cell surface. In this paper, the author gives a #review on applying IFN-α-inducible genes to determine type I interferon signature, which can be used to diagnose the SLE disease and other #autoimmune #diseases. 📝 Optimal Selection of IFN-α-Inducible Genes to Determine Type I Interferon Signature Improves the Diagnosis of Systemic Lupus Erythematosus — Veronique Demers-Mathieu. Full text is available 👇 https://lnkd.in/dbQNCgdW #medicine #health #research #science

The gut microbiome is a field of vast oppourtunities for research. I was curious on how the gut microbiome can potentially impact muscle mass. Although the current evidence is mainly pre-clinical trials, I think it is important to review. Click the link to read more

🌟 Exciting News. EpiDisease SL is thrilled to announce our collaboration with CSIC, Universidad Autónoma de Madrid, NUTRINSECT, Centre of Marine Sciences (CCMAR), and IMDEA Alimentación Food as part of the DiBaN consortium funded with an @European Innovation Council Pathfinder grant! 🌟 By joining this esteemed group, we will leverage our expertise in epigenetics and biomarkers to enhance the consortium's mission of tackling metabolic diseases and intestinal dysbiosis through innovative nutritional solutions. Together, we are committed to advancing research and developing effective interventions that will significantly improve public health. Stay tuned for updates on our journey! #EpiDisease #DiBaNConsortium #PublicHealth #T2D #MetabolicDiseases #Innovation www.epidisease.com https://lnkd.in/emDQwgS5

#HighlyCitedPapers   📝 Plasma Metabolic Disturbances in Parkinson’s Disease Patients — Gątarek, et al.   In this paper, the authors aimed (1) to identify metabolic alterations in plasma metabolome in subjects with Parkinson’s disease (PD) as compared with the controls; (2) to find new potential markers, some correlations among them; (3) to identify metabolic pathways relevant to the pathophysiology of PD.   Full text is available 👇 https://lnkd.in/gFeTT5tA   #medicine #health #research #science