A new clinical trial shows cytisinicline, combined with behavioral support, is a promising and well-tolerated treatment for adults aiming to quit vaping nicotine e-cigarettes. Participants treated with cytisinicline and behavioral support showed more continuous abstinence from from e-cigarette use compared to those treated with the placebo.
Read the full trial: https://lnkd.in/d6y6Ai3B#NJPA#Psychiatry#MentalHealth
Serotonin Syndrome is a potentially life-threatening condition caused by an excess of serotonin in the brain, often triggered by certain medications. In this video, Dr. Barness from Mindful Medicine breaks down the key signs, symptoms, and treatment options you need to know.
#mindfulmedicine#mentalhealthawareness#mentalhealthmatters#serotoninsyndrome#psychiatry
It's So Hard To Understand That 60% Of DSM-5 Was Manipulated By Big Pharma And How Long And Irreversible Physical, Mental And Emotional Damage We Have To Cause To Break What Scientific Proven Doesn't Work!!!
Evidence does not confirm that lithium prevents suicide: a reply to Bschor et al
Joanna Moncrieff 1, Martin Plöderl 2 3, Zainab Nabi 1, Jacki Stansfeld 1, Lisa Wood 1
Pharmacotherapy is an effective treatment modality across psychiatric disorders. Nevertheless, many patients discontinue their medication at some point. Evidence-based guidance for patients, clinicians, and policymakers on rational discontinuation strategies is vital to enable the best, personalized treatment for any given patient. Nonetheless, there is a scarcity of guidelines on discontinuation strategies. In this perspective, we therefore summarize and critically appraise the evidence on discontinuation of six major psychotropic medication classes: antidepressants, antipsychotics, benzodiazepines, mood stabilizers, opioids, and stimulants. For each medication class, a wide range of topics pertaining to each of the following questions are discussed: (1) Who can discontinue (e.g., what are risk factors for relapse?); (2) When to discontinue (e.g., after 1 year or several years of antidepressant use?); and (3) How to discontinue (e.g., what's the efficacy of dose reduction compared to full cessation and interventions to mitigate relapse risk?). We thus highlight how comparing the evidence across medication classes can identify knowledge gaps, which may pave the way for more integrated research on discontinuation.😡 American Psychiatric AssociationInstitute of Psychiatry, Psychology & NeurosciencePsychedelic SupportPsychology TodayInstitute of Psychiatry, Psychology & NeuroscienceJAMA PsychiatryAmerican Board of Sports and Performance PsychiatryMultidisciplinary Association for Psychedelic Studies (MAPS)Psychedelic SupportPsych Congress NP InstituteNeurodiversity in Business (NiB) - the Neurodiversity CharityNeuroscience NewsNeurodiverse Brains in the WorkplaceNeuroGifted®Neurodiversity Education AcademyThe Neurodiversity Awareness EventAutism Innovation Community Foundation... Maybe When You Experience It Yourself With A Love One, Then Maybe If Your EGO Doesn't Get In The Way You Will Understand!!! Remember The Extrapyramidal Effects And Invasive Irreversible Damage To The Kidney, Even Without Really Understand How Lithium Works!!! Maybe You Love So Much TESLA Vehicles That Blind Your Common Sense!!!
#Lithium reduced suicidality 49% in this new analysis of 13 randomized controlled trials (Caveat: Suicide was not the primary outcome in these studies):
https://lnkd.in/eK6dg5qB
Bottom Line: Don't avoid lithium to prevent suicidal overdose; the data suggests the opposite.
NEW: Carlat #Psychiatry News, with in depth coverage of the daily studies posted on this feed:
https://lnkd.in/es9s3KdU
The April episode features #MDMA therapy, #lithium, #PTSD, #bipolar, #clozapine, #schizophrenia, #ECT, and a circadian therapy for #depression
#Lithium reduced suicidality 49% in this new analysis of 13 randomized controlled trials (Caveat: Suicide was not the primary outcome in these studies):
https://lnkd.in/eK6dg5qB
Bottom Line: Don't avoid lithium to prevent suicidal overdose; the data suggests the opposite.
NEW: Carlat #Psychiatry News, with in depth coverage of the daily studies posted on this feed:
https://lnkd.in/es9s3KdU
The April episode features #MDMA therapy, #lithium, #PTSD, #bipolar, #clozapine, #schizophrenia, #ECT, and a circadian therapy for #depression
Dextromethorphan successfully augmented SSRI #antidepressants in this new, small RCT (it's an ingredient in the rapid acting Auvelity, where it is paired with bupropion):
https://lnkd.in/e3hzzE7M
The patients had not failed the SSRI, so it's really an enhancement study. They confirmed dextromethorphan reached "therapeutic" levels (0.5–5.9 ng/ml).
#psychiatry#pmhnp#depression
Consultant Psychiatrist at Al Amal Psychiatric Hospital | Forensic Psychiatry Expert | Addiction Specialist | Dedicated to Enhancing Mental Health Outcomes through Compassionate Care and Evidence-Based Practices
#Is_it_better_to_maintain_or_reduce?
When treating a patient with a longstanding history of schizophrenia on long-term antipsychotic polypharmacy, you may hesitate to reduce the treatment but also consider minimizing it. The key question: is it better to maintain or reduce?
A recent study sheds light on this by examining the effects of switching from antipsychotic polypharmacy (APP) to monotherapy (APM). Results showed that patients on long-term polypharmacy experienced significant reductions in movement disorders, metabolic issues, and certain side effects after switching to monotherapy. This offers valuable insight for optimizing treatment.
Read more here :
Should you continue #antipsychotic polypharmacy or lower to a single med in schizophrenia?
This 9-mth randomized trial found lower relapse rates and side effects (akathisia, parkinsonism, dyskinesia) in institutionalized #schizophrenia with antipsychotic reduction:
https://lnkd.in/eqZeX5pB
Here's the earlier results on psychosis outcomes:
https://lnkd.in/enhm-7WW#psychiatry
There are 3 ways to prevent depression after ECT:
1. CBT Therapy
2. #Lithium + nortriptyline (or SNRI)
3. Maintenance #ECT (eg, monthly)
In this large study of 19,944, maintenance ECT lowered hospitalization rates by 60%:
https://lnkd.in/ecJrEZh5
After ECT, lithium and maintenance ECT cut the relapse rates in half.
#psychiatry
Dextromethorphan successfully augmented SSRI #antidepressants in this new, small RCT (it's an ingredient in the rapid acting Auvelity, where it is paired with bupropion):
https://lnkd.in/e3hzzE7M
The patients had not failed the SSRI, so it's really an enhancement study. They confirmed dextromethorphan reached "therapeutic" levels (0.5–5.9 ng/ml).
#psychiatry#pmhnp#depression
