Mike Hines PhD’s Post

Part of nutrition care for oncology pt is to address the side effect from the medical therapies and give nutritional recommendations based on that. Side effects could vary from typical to unusual, such as hiccups:D https://lnkd.in/eCC3_aNg * This site was mentioned in Catalyst course. #oncology #medical #medicaleducation

#TrendingWithImpact: On March 3, 2024, researchers from Pusan National University published a new research paper in Aging's Volume 16, Issue 5, entitled, “FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet.” “This discovery unveils a potential novel molecular target for therapeutic strategies against hepatic steatosis during the aging process [...]” #PressRelease: https://lnkd.in/e4nr7Gyi #aging #hyperlipidemia #steatosis #diet #agingresearch #openaccess #openscience #peerreviewed #journal #publication #publishing #meded

Why Doctors Should Learn More About the Microbiome? #Mysummary The recent The International Microbiota Observatory report from the Biocodex Microbiota Institute highlights a major gap in patient education around the microbiome. Only 44% of people said their doctor informed them about behaviors that can preserve a balanced gut microbiome. Even more concerning, just 33% were told that antibiotics could disrupt this balance, despite 66% of people being aware of antibiotics' impact. The consequences of this knowledge deficit are clear. A staggering 95% of people who received microbiome guidance from their healthcare provider adopted behaviors to support a healthy gut, compared to only 57% of those who didn't get that advice. As Murielle Escalmel, Scientific Communication Director at the Biocodex Microbiota Institute, explains: "The survey has shown that patients who receive information from healthcare professionals have a healthier approach to their microbiota. What's more, it triggers virtuous behavioral cycles. So we need to give healthcare professionals more support to fully integrate the microbiome into the patient care pathway." #Mythoughts In my opinion, medical education needs a microbiome overhaul. Doctors must learn how to counsel patients on diet, probiotics, avoiding unnecessary antibiotics, and other strategies to nurture a healthy gut. They should also stay up-to-date on emerging microbiome-based treatments as this field rapidly evolves. At the end of the day, the microbiome impacts so many aspects of our health not just the gut-related ones! HAPPY to hear your THOUGHTS and stay POSITIVE! #Myinspiration “Magic is believing in yourself, if you can do that, you can make anything happen.” Johann Wolfgang Von Goethe You can check out what The Lancet Gastroenterology and Hepatology is saying about the microbiome here: https://lnkd.in/epXFb5P9 Rob Brierley thanks for sharing! #microbiome #science #biology #health #pharma #diet #nutrition #probiotics #therapeutics #startup #biotech

Understanding the gut-brain axis and the role of α-synuclein in Parkinson's disease (PD) has become a focal point in recent research. By exploring the influence of polyphenols on gut microbiota and α-synuclein aggregation, researchers aim to develop therapeutic strategies for PD, potentially slowing its progression. The interplay between dietary polyphenols, gut health, and α-synuclein pathology presents a new frontier in PD treatment. Hashtags: #ParkinsonsDisease #GutBrainAxis #Polyphenols #Biohacking #HealthResearch Read more here: https://lnkd.in/eHwgyH57 BioMedHack.com is your leading source for the latest news, breakthroughs, and insights in medicine, biohacking, and alternative medicine. Our mission is to help you live healthier and longer by bringing you cutting-edge information and expert advice. Follow us on Facebook, Instagram, and X.

🌟 In the ongoing quest for better treatments for diabetic wounds, a groundbreaking study published in *Medical Gas Research* sheds light on the potential of nitric oxide-based therapies. Diabetes mellitus affects over 536.6 million adults worldwide, with complications like diabetic foot ulcers leading to limb amputations and hospital admissions. These ulcers are a significant cause of death and disability, underscoring the need for effective wound care solutions. The study presents a comprehensive review of the current evidence supporting the role of nitric oxide (NO) in wound healing, particularly in the context of diabetes. NO, a multifunctional gasotransmitter, plays a critical part in the normal wound healing process. Research indicates that NO-based therapeutics could be key in managing diabetic wounds. Animal models have shown promising results, with some NO-based treatments accelerating wound healing and reducing inflammation. However, translating these findings to human clinical practice presents challenges due to differences in wound healing processes between species. 🔗 Read the full article here: [Nitric oxide-based treatments improve wound healing] https://lnkd.in/gNuBDFJY About the Journal: Medical Gas Research is indexed in MEDLINE, Emerging Sources Citation Index, PubMed and etc. 2023 JCR IF: 3.0, Q2 in MEDICINE, RESEARCH & EXPERIMENTAL. #Diabetes #WoundHealing #MedicalInnovation #NitricOxide #Healthcare #Research

Keen to hear your thoughts… Sarcopenia vs myopenia terminology when it comes to nutrition research describing skeletal muscle loss in clinical conditions. Let’s first look at the definitions. Sarcopenia is defined as an age-related loss in skeletal muscle mass and function. Myopenia is described as the presence of clinically relevant muscle wasting due to illness at any age. I’ve noticed recently, in the last few years, an increasing number of clinical nutrition research is using sarcopenia as the definition for skeletal muscle loss. Particularly in critical illness. Given the definition above, is this the correct and or most accurate use of the term sarcopenia? I don’t think so. Why do you ask? Well, what terminology do you use for younger patients? What about muscle wasting due to, immobility, cancer, chronic heart failure, lung and kidney diseases? All these conditions can occur at any age. While it’s great to see more research being done in this space to highlight the importance of the negative clinical and functional effects that muscle wasting has on patients in hospital, using the term sarcopenia may be confusing both scientific and medical communities. Instead, I believe the term myopenia may be a better definition. This terminology can encompass a large range of disease related levels of muscle loss, including sarcopenia. Let me know your thoughts in the comments below. Open to a constructive discussion around this topic. For more, see this editorial by Fearon, et al (2011). PMC3063883. Image Source: Fearon et al (2011) #terminology #myopenia #sarcopenia #criticalillness #yourthoughts Note: These opinions are my own, and are not the opinions of the companies I work for or have worked for in the past.

The spot urine magnesium test measures the amount of magnesium in a single urine sample. This test can provide valuable insights into your body's magnesium levels and help diagnose various health conditions. Purpose: - Kidney Function: It helps assess kidney function, as the kidneys play a crucial role in regulating magnesium levels in the body. - Magnesium Deficiency or Excess: It can help diagnose conditions related to magnesium deficiency (hypomagnesemia) or excess (hypermagnesemia). - Electrolyte Imbalance: It aids in identifying electrolyte imbalances that can affect overall health. Procedure: - Sample Collection: A random urine sample is collected, usually in a clean container provided by the healthcare provider. - Testing: The urine sample is analyzed to measure the concentration of magnesium. Interpretation: - Normal Range: The normal range for magnesium in a random urine sample is typically 22-130 mg/g creatinine. - High Levels: Elevated magnesium levels in urine may indicate excessive dietary magnesium intake, kidney disease, or issues with magnesium regulation. - Low Levels: Low magnesium levels can be due to insufficient dietary intake, gastrointestinal losses, or certain medications. Understanding your urine magnesium levels can help in diagnosing and managing conditions related to kidney function, electrolyte balance, and overall metabolic health. #MedicalLaboratoryTechnology #Microbiology #Phlebotomy #LaboratoryTesting #DiagnosticTesting #HealthcareProfessional #MedicalTesting #ClinicalLaboratory #BiomedicalScience #HealthcareIndustry #MedicalScience #LaboratoryMedicine #ClinicalMicrobiology #InfectionControl #PhlebotomyTechnician #MedicalLabTechnician #MicrobiologyLab #ClinicalLab #HealthcareCareer #MedicalCareer #ScienceCareer #COVID19Testing #Virology #Bacteriology #Parasitology #MolecularDiagnosis #GeneticTesting #Cytology #Histopathology #Immunology #Serology

RESVERATROL AND VASCULAR HEALTH: Evidence from clinical studies and mechanisms of actions related to its metabolites produced by gut microbiota. This review aims to summarize the main findings from clinical trials on the effects of resveratrol interventions on endothelial and vascular outcomes and review potential mechanisms interesting the role of gut microbiota on the metabolism of this molecule and its cardioprotective metabolites.

Improvement of HbA1c, Weight and Fatty Liver by Short Treatment of Imeglimin (Twymeeg) Takafumi Kawata, Hiroshi Bando*, Yoshinobu Kato, Hisako Yamashita, Yoshikane Kato, Katsunori Ogura #Asploro Journal of Biomedical and Clinical Case Reports ISSN: 2582-0370 Article Type: #CaseReport DOI: https://lnkd.in/gQZR53_6 HTML: https://lnkd.in/gAUNJt4K Abstract The patient is a 55-year-old male with type 2 diabetes (T2D). In his 20s, 30s, and 50s, his body weight was 80 kg, 95 kg, and 90 kg, respectively. HbA1c was 10.9% in March 2023, and he was prescribed imeglimin (Twymeeg) as an oral hypoglycemic agent (OHA). HbA1c decreased to 9.3%, 7.2%, and 6.8% within just 3 months. His body weight also decreased from 86 kg to 82 kg during this period. Liver function tests showed improvement between March and May 2023, with AST decreasing from 54 to 24 U/L, ALT from 121 to 28 U/L, and GGT from 45 to 18 U/L, respectively. This suggests an improvement in fatty liver. #Type2Diabetes, #imeglimin, #Twymeeg, #LowCarbohydrateDiet, #JapanLCDPromotionAssociation, #TrialsofIMegliminforEfficacyandSafety, #TokushimaUniversity

Can nature rival modern medicine? A fascinating new study tested chlorogenic acid—a natural compound commonly found in Yerba Mate—on diabetic mice and uncovered some striking results. Researchers found that chlorogenic acid: Improved glucose tolerance and insulin sensitivity Reduced liver fat by enhancing fat breakdown and transport Lowered inflammation and oxidative stress Restored gut health by increasing beneficial bacteria, like Lactobacillus and Blautia The most notable finding? The effects were similar to Metformin, one of the most trusted medications for managing diabetes. This research highlights the powerful role natural solutions may play in improving metabolic health. 🔗 Full study here: https://lnkd.in/djtr-bSM Would you consider natural interventions like this as part of your health approach?