COVID-19 Targets Obesity

COVID-19 attacking the obese and government policy has made it worse

Last week I reviewed four recent studies which estimated that 150 million people worldwide were being pushed into poverty by the government's response to COVID-19.

Meanwhile, the billionaires, politicians, and Zoomers fared much better, possibly even benefiting from the government's low-interest policy and support for the stock and bond markets.

This week I investigated the relationship between COVID-19 and obesity. What I find is truly scary. Tell me if you feel the same at the end of this article. Also if you find any additional research for and against what I have written please feel free to add it to the comments.

 What is obesity?

According to Wikipedia, “obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health. It is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. There have also been links found between obesity and depression. Research shows that maintaining weight loss after dieting over the long term proves to be rare.”

“Diet quality can be improved by reducing the consumption of energy-dense foods, such as those high in fat or sugars, and by increasing the intake of dietary fiber. However, studies have found an inverse relationship between energy density and energy cost of foods in developed nations. Low-income populations are more likely to live in neighborhoods that are considered "food deserts" or"food swamps" where nutritional groceries are less available.”

“Obesity is a leading preventable cause of death worldwide, with increasing rates in adults and children. In 2015, 600 million adults (12%) and 100 million children were obese in 195 countries. Authorities view it as one of the most serious public health problems of the 21st century.”

Obesity afflicts more than 20% of adults in Americans

Guidelines related to obesity are issued by the CDC, which gives these definitions:

• Overweight means a body mass index (BMI) > 25 kg/m2 but < 30 kg/m2
• Obesity means a BMI ≥30 kg/m2 but < 40 kg/m2
• Severe obesity is a BMI of ≥40 kg/m2

A recent CDC study in America showed that "All states and territories had more than 20% of adults with obesity”

Education level is a significant determinant of the risk of obesity

The US Behavioral Risk Factor Surveillance System under the CDC conducts more than 400,000 telephone surveys per year across all 50 states and concluded that about 34% of those who had not graduated from college grades self-reported as obese, which was much lower at 25% for college grads.

 Guidelines about how Americans should refer to obesity

The CDC refers to notes on language and images to use and not use concerning obesity.

• They recommend you say, "adults with obesity" or "20% of children ages 12-19 have obesity."
• They recommend you should NOT say "obese adults" nor "20% of children are obese."

These guidelines originate from the Guidelines for Media Portrayals of individuals Affected by Obesity. What follows comes from this report, "Consider carefully whether terminology and language used to describe body weight could be offensive to persons with obesity and how the intended audience will interpret this language. Avoid using potentially pejorative adjectives or adverbs when describing people who are affected by excess weight or obesity and language that implies moral judgments or character flaws of this population."

Early on, governments knew the relationship between COVID-19 death and obesity

In July 2020, the UK govt issued a press release that highlighted a research study that found that for people with a BMI of 35 to 40, the risk of death from COVID-19 increases by 40%, and those with a BMI over 40 by 90%, compared to those not living with obesity. Other data found that in intensive care units, 7.9% of critically ill patients with COVID-19had a BMI over 40 compared with 2.9% of the general population. Almost two-thirds (63%) of adults in England are overweight or obese, with people aged 55 to 74, those living in deprived areas, and certain black, Asian, and minority ethnic groups more severely affected.

In the US in August 2020, a meta-study of peer-reviewed papers found that people with obesity who contracted SARS-CoV-2 were 113% more likely than people of healthy weight to land in the hospital, 74% more likely to be admitted to an ICU, and 48% more likely to die.

Italy was an early warning about the deadliness of COVID-19

Wikipedia reveals that COVID-19 spread to Italy on 31 January 2020, with the first deaths on 22 February. By the beginning of March, the virus had spread to all regions of Italy.

The economic shutdown meant less exercise and more energy-dense (read: fattening) foods

One study reviewed the impact of the breakdown of supply chains. This breakdown limited access to fresh foods, leading to an abundance of processed and ultra-processed foods, which are energy dense and contain saturated fat, sodium, and sugar. Ultra-processed foods have previously been found to be directly linked to obesity and adverse health outcomes. Due to the low cost of ultra-processed food, this supply chain breakdown hit the population's lower-income segments hardest. Lockdowns reduced the walking and exercise time of adults, causing a rise in obesity. Reduced energy expenditures and increased ultra-processed foods have likely contributed to significant weight gain. To make matters worse, health professionals knew that individuals with obesity are likely to face reductions in vaccines' effectiveness through mechanisms similar to those responsible for greater primary infection risk.

Government shelter-in-place orders cost about 7 kg of permanent weight gain

A recent study showed that the cost of complying with the US government's shelter-in-place (SIP)orders was a steady weight gain of 0.27 kg(0.6 lbs)every ten days irrespective of geographic location or comorbidities of the subjects studied. Thistranslatesintoabout 0.7 kg (1.5 lbs)of weight gain every month, which means that this policy alone could have caused the average American to gain about 7 kg (15 lbs). Additional research shows that this weight gain is likely to be permanent.

 Obesity is deadly

One study showed that before the pandemic, around 2.8 million people worldwide died each year because of being overweight, from conditions that stem from it, including heart disease, stroke, and diabetes.

 COVID-19 deaths per million were 10x higher in above-average obesity countries

We accessed World Health Organization's data on obesity and COVID-19 disease data from Wikipedia to rank 171 countries on these two measures. We split the list of countries in half; of the 85 countries with below-average obesity rates, the lowest were: Vietnam, Bangladesh, Cambodia, India, Nepal, and Japan. Of the 86 countries with the highest obesity, the worst were: United States, Jordan, Saudi Arabia, Turkey, and Egypt.

 The table below shows that above-average countries had 9x more cases per 1,000,000 people and10x more deaths per 1,000,000 people. The death rate for those infected was only a bit higher, possibly because those who got COVID-19 in the below-average obesity countries were the rare obese citizen.

A widely available study shows a clear link between obesity and death from COVID-19

Don't take my word for it; a recent study from the World Obesity Federation also found that Covid-19 death rates are ten times higher in countries where more than half of the adult population is classified as overweight."Of the 2.5 million covid-19 deaths reported by the end of February 2021,2.2 million were in countries where over half the population is classified as overweight—defined as a body mass index above25."The report found linear correlations between a country's covid-19 mortality and the proportion of overweight adults. They also found that not a single country with less than 40% of the population overweight and high death rates, and no country with a high death rate has less than 50% of their population overweight. The report highlighted that 68% of the US population was overweight compared to only 18% in Vietnam.

A November 2020 paper referenced 22 previously published peer-reviewed articles linking obesity and its impact on COVID-19 outcomes. It concluded that obesity had a substantial effect on risk related to COVID-19. It recommended that obese patients receive more aggressive preventative measures.

 Why are the obese so vulnerable to COVID-19?

One recent study proposed the following seven potential reasons why COVID-19 could more hard-hit the obese

1. Obesity-associated inflammation and its impact on SARS-CoV-2 infection
2. Cellular immune function is impaired in obesity
3. Excess fat deposition disrupts lymphoid tissue architecture and integrity
4. Insulin resistance negatively impact immune function
5. Leptin resistance in obesity impairs immune functioning
6. Altered ACE2 expression in obese subjects may impact COVID-19 disease severity
7. Role of coagulopathy /thrombosis in SARS-CoV-2 pathogenesis

If you have made it this far in the article, then you probably feel like you should get up and go for a walk. I will see you there!