Generic Name: fluticasone
Brand Name: Flonase, Flonase Allergy Relief
Drug Class: Corticosteroids, Intranasal
What is fluticasone, and what is it used for?
Fluticasone is a man-made corticosteroid used for the management of nasal symptoms of seasonal or perennial, allergic and non-allergic rhinitis in adults and children of 4 years of age and older. Safe and effective use of fluticasone has not been established for children under the age of 4.
The exact mechanism of action of fluticasone is not known; however, it stimulates glucocorticoid receptors in humans that produces a potent anti-inflammatory response. Fluticasone also works on multiple cells and mediators that are responsible for the inflammatory symptoms of allergic rhinitis (sneezing, runny nose, etc).
The FDA approved fluticasone in October 1994.
What are the side effects of fluticasone?
Side effects of fluticasone include:
- headache,
- sore throat,
- nosebleeds,
- nasal burning or nasal irritation,
- nausea,
- vomiting,
- asthma symptoms, or
- cough.
Some children may experience growth suppression from use of inhaled steroids.
What is the dosage for fluticasone?
- Adults: The recommended dosing is 2 sprays per nostril daily. The maximum dose is 200 mcg/day (4 sprays). Maintenance therapy is 1 spray in each nostril daily.
- Adolescents and children 4 years of age and older: the recommended dosing is 1 spray per nostril daily (total dose 100 mcg.) Patients that do not respond adequately may increase to two sprays in each nostril once a day. The maximum dose is 200 mcg/day.
Which drugs interact with fluticasone?
Ritonavir (Norvir) and ketoconazole (Nizoral, Extina, Xolegel, Kuric) increase fluticasone levels in the body by delaying its metabolism (elimination). It is not clear how important this effect is.
SLIDESHOW
See SlideshowPregnancy and breastfeeding
- There are no adequate studies of fluticasone to determine its safety and effectiveness in pregnant women.
- It is not known whether fluticasone enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.
What else should I know about fluticasone?
- Fluticasone propionate nasal spray is available as a 16 gm bottle, providing a total of 120 sprays. Each spray contains 50 mcg of fluticasone propionate.
- Fluticasone propionate should be store between 4 C and 30 C (39 F and 86 F).
- Brand names for fluticasone propionate are Flonase and Flonase Allergy Relief.
- Flonase is available by prescription and over-the-counter (OTC).
Health News
- More of America's Pets Are Overdosing on Stray Coke, Meth
- GLP-1 Zepbound Is Approved As First Drug For Sleep Apnea
- Feeling Appreciated by Partner is Critical for Caregiver's Mental Health
- Tips for Spending Holiday Time With Family Members Who Live with Dementia
- The Most Therapeutic Kind of Me-Time
- More Health News »
Summary
Fluticasone propionate nasal spray is a corticosteroid prescribed for the management of symptoms of seasonal or perennial allergic and non-allergic rhinitis. Side effects of fluticasone include headache, sore throat, nosebleeds, nasal burning or nasal irritation, nausea, vomiting, asthma symptoms, or cough. Consult with your doctor if pregnant or breastfeeding.
Multimedia: Slideshows, Images & Quizzes
-
Allergies: 10 Ways to Reduce Mold Allergies
WebMD shows you 10 ways to fight the fungus and reduce mold allergy symptoms from dust masks to bottles of bleach.
-
Common Allergies: Symptoms and Signs
What are allergies? Pollen, food, perfumes, and many more things can provoke allergy symptoms. Allergies are an overreaction of...
-
The Most Common Food Allergies for Kids and Adults
What common food allergens cause the most problems for adults and children? See this list of common food allergies and learn to...
-
Allergies Quiz: Symptoms & Home Remedies
What are the causes of allergies? This online quiz challenges your knowledge of common food and household allergens,...
-
10 Signs Your Allergies Are Out of Control
Learn 10 signs your allergies are out of control. See these surprising allergy symptoms and find out how to get relief for...
-
10 Worst Cities for Spring Allergies
See pictures of the top 10 "spring allergy capitals", according to the Asthma and Allergy Foundation of America (AAFA). From...
-
When Animal (Allergies) Attack: Pet Allergy Symptoms, Treatment
How do you control and relieve pet allergies? How do you prevent pet allergies? Learn dog and cat allergy symptoms, the cause of...
-
Allergies: Common Plants and Trees That Trigger Allergies
Find out more about which plants and trees might be producing pollen that is causing your itchy eyes and a runny nose.
-
Nasal Irrigation: Natural Relief for Cold & Allergy Symptoms
Clogged sinuses and congestion bothering you? Nasal irrigation can relieve sinus symptoms associated with colds and allergies....
-
Dangerous Allergies: Anaphylaxis and Life-Threatening Allergy Triggers
Common allergy triggers may provoke anaphylaxis. Hives, tongue swelling, face swelling, rashes, low blood pressure, rapid and...
-
Nasal Allergy Attack: Causes, Triggers, Treatments
Nasal allergies are a common problem that affects millions of people. An allergist can recommend the best allergy nasal sprays...
-
Pictures of Allergy Relief Tips at Home: AC Filters, Electronic Air Cleaners, and More
Learn how a combination of medication, preventing allergens, and allergy relief products can reduce allergy symptoms and help you...
-
Allergies: Can You Learn to Breathe Better?
Can you learn new techniques to breathe better? Healthy breathing helps you maintain the right balance of oxygen and carbon...
-
Home Allergy Quiz: Is Your Home Allergy-Proof?
Take this home allergy quiz and test your knowledge on allergens, dust mites, pollens and more to see how allergy-proof your home...
-
Top Items for Your Allergy Relief Kit
Be prepared for your next allergy attack no matter where you are. WebMD shows you what you need in your allergy kit to help...
-
12 Natural Ways to Defeat Allergies
Allergies making you miserable? WebMD shows you a dozen natural allergy treatments, from fresh fruit and vitamin D to acupuncture...
Related Disease Conditions
-
How Long Does an Allergic Reaction Last?
Allergic reactions may last for varying lengths of time. They may take a few hours to a few days to disappear. If the exposure to the allergen continues, such as during a spring pollen season, allergic reactions may last for longer periods such as a few weeks to months.
-
Cough: 19 Tips on How to Stop a Cough
Coughing is a reflex that helps a person clear their airways of irritants. There are many causes of an excessive or severe cough including irritants like cigarette and secondhand smoke, pollution, air fresheners, medications like beta blockers and ACE inhibitors, the common cold, GERD, lung cancer, and heart disease.Natural and home remedies to help cure and soothe a cough include staying hydrated, gargle salt water, use cough drops or lozenges, use herbs and supplements like ginger, mint, licorice, and slippery elm, and don't smoke. Over-the-counter products (OTC)to cure and soothe a cough include cough suppressants and expectorants, and anti-reflux drugs. Prescription drugs that help cure a cough include narcotic medications, antibiotics, inhaled steroids, and anti-reflux drugs like proton pump inhibitors or PPIs, for example, omeprazole (Prilosec), rabeprazole (Aciphex), and pantoprazole (Protonix).
-
Chronic Rhinitis
Chronic rhinitis (non-allergic rhinitis) causes runny nose, sneezing, nasal itching, and congestion. Post-nasal drip is the drainage of mucus from the sinuses into the throat. Treatment includes over-the-counter (OTC) medications.
-
Sinusitis
Sinus infection (sinusitis) is caused by allergies, infection, and chemicals or other irritants of sinuses. Signs and symptoms include headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.
-
Allergy
An allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. When these allergens come in contact with the body, it causes the immune system to develop an allergic reaction in people who are allergic to it. It is estimated that 50 million North Americans are affected by allergic conditions. The parts of the body that are prone to react to allergies include the eyes, nose, lungs, skin, and stomach. Common allergic disorders include hay fever, asthma, allergic eyes, allergic eczema, hives, and allergic shock.
-
Mucus
Mucus is a standard substance produced by lining tissues in the body. Excess mucus or yellow, green, brown, or bloody mucus may indicate a problem. Mucus production may increase when allergies, a cold, flu, cough, or sore throat occur. Antihistamines and cold and flu medications may help alleviate excess mucus. A neti pot may be used to decrease nasal congestion and clear mucus.
-
What Are the 4 Types of Allergic Reactions?
Allergists recognize four types of allergic reactions: Type I or anaphylactic reactions, type II or cytotoxic reactions, type III or immunocomplex reactions and type IV or cell-mediated reactions.
-
What Are the 20 Most Allergic Foods?
Common food allergies include milk, eggs, peanuts, tree nuts, sesame, soy, fish, shellfish, and wheat. Here are 20 of the top food allergies.
-
Hay Fever
Hay fever (allergic rhinitis) is an irritation of the nose caused by pollen and is associated with the following allergic symptoms: nasal congestion, runny nose, sneezing, eye and nose itching, and tearing eyes. Avoidance of known allergens is the recommended treatment, but if this is not possible, antihistamines, decongestants, and nasal sprays may help alleviate symptoms.
-
Cold, Flu, Allergy Treatments
Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the symptoms, which symptoms one wishes to relieve, and the active ingredients in the OTC product. Taking products that only contain the medications needed for relieving your symptoms prevents ingestion of unnecessary medications and reduces the chances of side effects.
-
How Long Does It Take for Allergic Conjunctivitis to Go Away?
Without treatment, allergic conjunctivitis symptoms could last the entire time that your critical allergen is present — which can vary greatly.
-
How Do You Calm Down an Allergy Attack?
Here are thirteen tips to calm an allergy attack and put an end to constant sneezing, itching, and congestion.
-
What Causes Sudden Allergies in Adults?
Can you develop allergies as an adult? Learn about what causes sudden adult-onset allergies and how you can recognize the symptoms.
-
Why Won’t My Allergy Symptoms Go Away?
Allergies happen when your body's immune system reacts to certain substances as though they are harmful. Allergy symptoms may not go away unless you avoid your triggers, stick to your medications, find the right combination of medications, and consider surgery.
-
Allergic Cascade
The allergic cascade refers to allergic reactions that happen in the body in response to allergens. A variety of immune cells and chemical messengers participate in the allergic cascade. Symptoms of the allergic cascade range from mild swelling and itching to full-blown anaphylactic shock. Allergen avoidance and medications are used to prevent or treat allergies.
-
Sinus Infection vs. Allergies
Both sinus infections and allergies (allergic rhinitis) cause symptoms such as runny or stuffy nose and fatigue. Sinus infection (known as sinusitis) is inflammation of the sinuses, caused by infection from bacteria, viruses, and/or fungi (molds). Allergic rhinitis occurs when certain allergies cause nasal symptoms. When a person with allergies breathes in an allergen, such as pollen, dust, or animal dander, symptoms such as runny or stuffy nose, itching, sneezing, and fatigue occur.
-
What Are the Best Treatments for Allergic Conjunctivitis?
Learn what medical treatments can ease allergic conjunctivitis symptoms and help speed up your eye allergy recovery.
-
What Causes Allergy Flare-ups?
During certain seasons, allergies can make you miserable. Learn what causes allergy flare-ups during spring and summer.
-
Allergy Treatment Begins at Home
Avoiding allergy triggers at home is one of the best ways to prevent allergy symptoms. Controlling temperature, humidity, and ventilation are a few ways to allergy-proof the home. Cleaning, vacuuming, and using HEPA air filters also helps control allergies.
-
Is Allergic Conjunctivitis the Same as Conjunctivitis?
Allergic conjunctivitis may occur along with sneezing, runny nose, or sinus headache. Many people also find that they are tired and feel agitated.
-
COVID-19 vs. Allergies
Though there is some overlap in allergy and COVID-19 signs and symptoms there are also significant differences. Symptoms that they have in common include headache, fatigue, tiredness, shortness of breath, wheezing, and sore throat. Fever does not occur with allergies but is one of the defining symptoms of COVID-19 infections.
-
Drug Allergy
Drug or medication allergies are caused when the immune system mistakenly creates an immune response to a medication. Symptoms of a drug allergic reaction include hives, rash, itchy skin or eyes, dizziness, nausea, diarrhea, fainting, and anxiety. The most common drugs that people are allergic to include penicillins and penicillin type drugs, sulfa drugs, insulin, and iodine. Treatment may involve antihistamines or corticosteroids. An EpiPen may be used for life-threatening anaphylactic symptoms.
-
What Are the Symptoms of Ragweed Allergy?
The common symptoms of ragweed allergy are sneezing, runny nose, itchy, watery red eyes, headache, nasal congestion, eye swelling, rashes and coughing.
-
What Foods Cause Oral Allergy Syndrome?
Oral allergy syndrome, also called pollen food allergy syndrome or PFAS, is a type of food allergy caused by certain allergens found in both pollen and raw vegetables and fruits and some nuts. Foods that cause oral allergy syndrome include those in the birch, grass and ragweed families.
Treatment & Diagnosis
- Allergies FAQs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Medication Disposal
- Do Allergy Drugs Interact with Synthroid?
- Generic Drugs, Are They as Good as Brand-Names?
Medications & Supplements
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- Drug Interactions
- cetirizine (Zyrtec, Zyrtec Allergy, Zyrtec Hives)
- cocaine
- Side Effects of Flonase (fluticasone)
- What Are the Benefits of An Aerosol Treatment?
- Xyzal (levocetirizine dihydrochloride)
- ipratropium
- Nasal Allergy Medications
- Side Effects of Breo Ellipta (fluticasone and vilanterol)
- Trelegy Ellipta (fluticasone furoate)
- Dymista (azelastine hydrochloride and fluticasone propionate)
- budesonide nasal inhaler (Rhinocort Allergy, Rhinocort Aqua)
- loratadine and pseudoephedrine (Alavert Allergy & Sinus, Claritin-D, Claritin-D 24 hour)
- Zinc for Colds: Lozenges & Nasal Sprays
- fluticasone furoate nasal spray (Veramyst)
- Side Effects of Flovent (fluticasone propionate) oral inhaler
- Advair Diskus, Advair HFA (fluticasone and salmeterol oral inhaler)
- fluticasone propionate oral inhaler (Flovent)
- Beconase AQ (beclomethasone) Side Effects, Warnings, and Drug Interactions
- beclomethasone dipropionate nasal inhaler-spray
- fluticasone furoate and vilanterol inhalation powder (Breo Ellipta)
- Spiriva
- Cutivate (fluticasone propionate)
- brompheniramine/dextromethorphan/phenylephrine
- flunisolide nasal spray, Aerospan (Nasalide, Aerobid, Aerobid HFA are discontinued)
- Advair Diskus (fluticasone propionate and salmeterol inhaler) Side Effects, Warnings & Interactions
- fluticasone propionate (Cutivate)
- Does Immunotherapy Work for Allergies?
- fluticasone hfa inhaler - oral
- ArmonAir Digihaler (fluticasone propionate inhalation powder)
- Side Effects of Veramyst (fluticasone)
- ArmonAir RespiClick (fluticasone propionate)
- fluticasone disk inhaler - oral, Flovent Rotadisk
Prevention & Wellness
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.