Research Institute of Molecular Pathology (IMP)

Are you a #postdoc with an innovative vision for starting your own lab in #Syntheticbiology, #Genomics, #GeneRegulation, #Development, #Cancer, #Immunology or #InfectionBiology? The IMP is inviting applications for group leader positions (similar to assistant professors): https://lnkd.in/dEpPb8Qq This is an opportunity to join a leading life science research institute that will be fully aligned with supporting your research agenda and developing your international career in science. Please share if you know suitable candidates.

Immunotherapy has revolutionised cancer treatment in recent years, offering hope for previously incurable cancers by using the immune system to fight them. However, many cancers evade immune attacks, leading to treatment resistance. Scientists led by Anna Obenauf at the IMP now discovered the crucial role of a type of immune cell—inflammatory monocytes—in reactivating cancer-killing T cells within tumours. 🔬 The findings, published in the journal Nature, make monocytes a promising target to boost immunotherapies, potentially benefitting patients affected by a range of cancers, including melanoma, lung, pancreatic, and colorectal cancer. ➡️ Read more: https://lnkd.in/gBkyHGGD ➡️ Paper: https://lnkd.in/gKQcsY86 Guillem Estivill, Anais Elewaut, Vienna BioCenter, Nature Portfolio

📣 Ready to take the next step in your career? We’re #hiringnow and have plenty of exciting opportunities across various fields! 🔍 Check out our open positions: https://lnkd.in/dB7gWfQV

Industry or academia? IMP alumnus Jakob Fuhrmann (now Genentech) thinks that this is not a question to ask in 2024. Learn why and read a detailed account of Jakob's career, which may well inspire current students, in a new interview of our "alumni portraits" feature: 👉 https://lnkd.in/dGXsDw8Z What's more, Jakob is currently recruiting a PhD student - more at: https://lnkd.in/dgjwP6jS

Hundreds of genome's off-switches were just mapped by Alexander Stark's lab at the IMP. The precise control of gene activity is essential for cell specialisation and the development of healthy organisms. While our understanding of enhancers—DNA sequences that activate genes—has advanced significantly, silencers, which switch off gene activity, are much less understood, despite their equally critical role. A combination of technical challenges and research biases has made it difficult for scientists to locate silencers on a genome-wide scale—until now. Using the new method 'silencer-seq', the scientists identified more than 800 silencers in fruit flies. 🧬Now published in the journal Molecular Cell! ➡️ Read more: https://lnkd.in/dQXCeAD9 ➡️ Paper: https://lnkd.in/dfBf7ACv Cell Press, Vienna BioCenter, Lorena Hofbauer, PhD

📣 Looking for a new career opportunity? We’re #hiringnow! Whether you're passionate about research, animal care, administration, or exploring new challenges, we have exciting roles for every stage of your career. 🔍 Check out our open positions: https://lnkd.in/dB7gWfQV

📣 We’re #hiringnow! The Clausen lab is offering a fully-funded #postdoc position to study disease mutations affecting muscle protein lifespan in C. elegans. The project focuses on #proteostasis and age-related #myopathies in a collaborative, cutting-edge research environment. ➡️More information: https://lnkd.in/d3xfKHXn #postdocjobs

🎉 Congratulations to recent IMP graduates Filip Nemcko and Julian Ehrmann for winning this year’s Vienna BioCenter PhD Award for their outstanding doctoral theses at the Vienna BioCenter Phd Symposium! ➡️ More about their projects and all the awardees: https://lnkd.in/dPWjAF3t Vienna BioCenter

The next interview in our "IMPloyable Talent" series features Ulla Schellhaas, a recent graduate of the Vienna BioCenter PhD Program from the labs of Clemens Plaschka at the IMP and Stefan Ameres at the Max Perutz Labs Vienna. Ulla is a talented biochemist with expertise in RNA biology, and her research background and hands-on experience have prepared her for the transition into industry, where she is excited to combine her technical skills with strategic decision-making. She’s #OpenToWork and actively seeking roles that allow her to apply her knowledge to projects that drive societal impact. Reach out to connect with Ulla!

🌟 Relive the Birnstiel Award acceptance talks with us! This week, we will have the pleasure of welcoming our 2024 Birnstiel Awardees to the IMP, where they’ll present their groundbreaking research. We can’t wait to hear about their discoveries and celebrate their achievements! While we anticipate this year's presentations, let’s take a moment to revisit some of the inspiring highlights from past awardees. The most popular talk from 2023 is by Sam van Beljouw, awarded for his PhD work on the bacterial CRISPR-Cas system and the discovery of a remarkable protein complex named ‘Craspase’. Sam’s research revealed that when Craspase detects specific viral RNAs, it transforms into a protein-cutting complex that can even trigger bacterial “suicide” to prevent viral spread to neighboring cells. This complex is precise and self-regulating, cleaving both viral RNA and proteins, and holds promising applications for precision protein targeting, much like Cas9 does for DNA editing. Sam studied biomedical engineering at Eindhoven University of Technology, philosophy at Tilburg University, and earned a Master’s in molecular and cellular biotechnology from Wageningen University & Research before beginning his doctoral work at Delft University of Technology. His exceptional contributions have been recognised with a Kiemprijs from the Dutch Royal Society for Microbiology (KNVM). ➡️ Watch the talk here: https://lnkd.in/dD_VSDBC #PhD #Award #LifeSciences