🎉 NANOSIMS IS UP AND RUNNING 🎉 We have some fantastic news for the end of the year – the NanoSIMS 50 at CMCA, University of Western Australia, is up and running and has been upgraded to the capabilities of a NanoSIMS 50L! Please share this news with any of your users who require NanoSIMS. The new NanoSIMS-HR will also be arriving soon, with plans to have it up and running in the first half of 2025. If you have any questions please contact Paul at paul.guagliardo@uwa.edu.au
Centre for Microscopy Characterisation and Analysis - The CMCA
Research Services
Crawley, Western Australia 315 followers
Microscopy and microanalysis, building a national and international reputation through excellence
About us
The Centre for Microscopy, Characterisation and Analysis (CMCA) infrastructure platforms and highly-skill staff provide excellent support to advance Research collaborations and support industry developments which are the basis for cutting-edge advances. Our mission is to enable research excellence by providing world-class science infrastructure and expertise in Characterisation to researchers and industry. At the CMCA, you can apply its expertise to turn promising research into outstanding research.
- Website
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https://www.cmca.uwa.edu.au/
External link for Centre for Microscopy Characterisation and Analysis - The CMCA
- Industry
- Research Services
- Company size
- 11-50 employees
- Headquarters
- Crawley, Western Australia
- Type
- Educational
- Founded
- 1963
- Specialties
- Electron Microscopy: Analytical spectroscopy - Diffraction - Element mapping - Imaging - Tomography - X-ray microanalysis (WDS and EDS) - Cathodoluminescence imaging - STEM imaging - FIB-SEM; Optical Microscopy: Confocal, multiphoton and fluorescence - 3D photo-montaging - Laser microdissection - Live cell imaging - Automated digital histology - SIM and STORM super-resolution microscopy - FCS/FLIM; X-ray Microscopy: Microscale 3D imaging - In vivo live animal imaging - Volumetric data; Scanning Probe Microscopy: Confocal Raman microscopy - Atomic force microscopy - Nanoindentation - Scanning Tunnelling microscopy; Secondary Ion Mass Spectrometry (SIMS): NanoSIMS and large-geometry SIMS - Sub-μm imaging mass spectrometry - High-precision isotope ratios; Nuclear Magnetic Resonance (NMR) Spectroscopy: Analytical NMR - Multinuclear NMR - Biological and metabolomics NMR - Solid state NMR - NMR method development; Biological and Molecular Mass Spectrometry: Electron and chemical ionisation - Targeted pathway analysis - Metabolomics - High-resolution mass spectrometry; Cytometry: Flow cytometry - Fluorescence activated cell sorting (FACS) - Image-based cell sorting - Helios (CyTOF - Time of flight mass cytometry) - Luminex bead-based assays - Beckman Coulter counter Z2 particle/ cell counting and sizing - 10X Genomics Chromium Genome Solution - Liquid Handling system; NIF Bioimaging Facility: Flagship 9.4 T MRI - Multi-spectral fluorescence imaging - Bioluminescence imaging - X-ray micro CT; Data Management, Analysis and Visualisation (DMAV): Data analysis - Imaging processing and reconstruction; Specimen Preparation: Biological science - Cryogenic preparation - Physical sciences.
Locations
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Primary
35 Stirling Hwy
M0010, The University of Western Australia
Crawley, Western Australia 6009, AU
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QEII Medical Centre, 6 Verdun Street
Harry Perkins Institute of Medical Research
Nedlands, WA 6009, AU
Employees at Centre for Microscopy Characterisation and Analysis - The CMCA
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Paul Guagliardo
Senior Research Officer at Centre for Microscopy, Characterisation and Analysis at The University of Western Australia
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Diana Patalwala
Facility Fellow- Preclinical and Materials Imaging, National Imaging Facility, University of Western Australia
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Liisa Hirvonen
Senior Lecturer at The University of Western Australia
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Peta Clode
Specialist in bioscience imaging and analysis, at The University of Western Australia
Updates
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Centre for Microscopy Characterisation and Analysis - The CMCA reposted this
This is a first for RAPID and I believe a first for WA: in-state produced Zr89 used for imaging in WA. The story of Zr89 at RAPID is decades in the making, relying on the foresight and support of Heads of Department down and the hard work of unsung engineers, chemists, physicists and biologists essentially volunteering their spare time because they saw the value in these ideas. Its not in public health's remit to spend much time on self promotion, and so private industry will naturally take up most the oxygen here on Linkedin when it comes to radiopharma. There's too many of you to name, so this is a general shout-out to all those somewhat overlooked colleagues (past and present) who've played a part in Zr89 here in Perth. You've done a big thing and I'm pretty pleased to have worked with you.
The WA National Imaging Facility would like to announce that it has scanned the first patient in the ImmunoPET Mesothelioma study using [89Zr]Zr-DFOSq-Durvalumab across a series of three (3) timepoints. We are proud to collaborate with National Centre for Asbestos Related Diseases (NCARD), The University of Western Australia, UWA Institute of Respiratory Health and Sir Charles Gairdner Hospital Department of Nuclear Medicine and RAPID Labs to deliver this investigative project to show how PET-CT may identify PD-L1 expression in tumour sites. Funding for this study has been provided by Dust Diseases board, ICARE*, Charlies Foundation for Research and Asbestos Diseases Society of Australia PD-L1 is an important target in immunotherapy treatment of cancer and the use of [89Zr]Zr-DFOSq-Durvalumab imaging may assist to personalise treatments for mesothelioma. This project would not be possible without the following: Anna Nowak and Melvin Chin as Principal Investigators, WA NIF Co-Director Roslyn Francis as the Chief Investigator, with imaging expertise at WA NIF provided by our PET-CT Fellow Heidi Espedal, together with the support of Perth Radiological Clinic and clinical trials support and patient recruitment from Amber-Lee Phung. This novel tracer [89Zr]Zr-DFOSq-Durvalumab was developed by multi-disciplinary teams and NIF partners across Australia, including Austin Health, University of Melbourne, Peter MacCallum Cancer Centre, Olivia Newton-John Cancer Research Institute, Telix Pharmaceuticals Limited, AstraZeneca, and the research team at RAPID Laboratories at Sir Charles Gairdner Hospital (https://lnkd.in/gFSqUpQP) with the participation of our Radiochemistry Fellow Joseph Ioppolo. #NCRISImpact Australian Government Department of Education National Imaging Facility
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Centre for Microscopy Characterisation and Analysis - The CMCA reposted this
Yesterday we welcomed some of the wonderful donors, who donate much needed funds to Cancer Council Western Australia, for a tour of our human and preclinical facilities. It is through their generosity, and others like them, that we have been able to build an open-access facility dedicated to #research that will lead to better health outcomes for all of WA. Centre for Microscopy, Characterisation and Analysis - The CMCA The University of Western Australia
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Centre for Microscopy Characterisation and Analysis - The CMCA reposted this
Congratulations to our WA NIF Fellow Heidi Espedal on her presentation at #EANM24 on 'Early chemotherapeutic imaging response assessed by FDG-PET, T2 weighted and diffusion-weighted MRI in patient-derived endometrial cancer mouse models'. National Imaging Facility The University of Western Australia
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Are you interested in learning about what we do? Visit our new website to discover our four national nodes and areas of expertise. https://lnkd.in/gPXwrwu4
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Centre for Microscopy Characterisation and Analysis - The CMCA reposted this
Our latest article on bicontinous nanostructures is finally out!
Elucidating nanostructural organization and photonic properties of butterfly wing scales using hyperspectral microscopy | Journal of The Royal Society Interface
royalsocietypublishing.org
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Excellent opportunity to join a world-class research centre!
The UWA node of Microscopy Australia is offering an exciting role to work with a team of expert academic and professional staff to drive data management strategies within the facility. Details of the role can be found by visiting the UWA jobs website or by searching for “Microscopy Australia Data Specialist 518259”.
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Centre for Microscopy Characterisation and Analysis - The CMCA reposted this
Excellent presentation today from Joseph Ioppolo at the National Centre for Asbestos Related Diseases (NCARD) Annual Scientific Meeting, talking about the facilities and #expertise offered by WA NIF. The WA NIF is proud to support a number of #research projects being undertaken by #NCARD researchers #impact #ncris National Imaging Facility
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WA NIF Node is pleased to announce its newest piece of hot-lab equipment. This Von Gahlen shielded laminar flow hood enables safer handling and dispensing of PET medical isotopes in a clean air environment. It also features an automated dipper for the ion chamber, which is installed under the working bench alongside a shielded storage cabinet. This hood can also be used for basic radiopharmaceutical preparations to support Phase 1 PET imaging trials occurring on our new Siemens Vision PET/CT in the room just next door. For more information, contact us at nif@uwa.edu.au.
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Centre for Microscopy Characterisation and Analysis - The CMCA reposted this
In June 2024, The University of Western Australia and the Australian Safeguards and Non-Proliferation Office (ASNO) signed a research contract to develop critical nuclear safeguards capabilities. This initiative aligns with the objectives and technical priorities of the International Atomic Energy Agency (IAEA). The project will be carried out at UWA’s Centre for Microscopy, Characterisation and Analysis - The CMCA, utilizing advanced instruments, sophisticated analytical platforms such as SIMS, LA-ICP-MS, and FIB-SEM, and a state-of-the-art clean laboratory. This agreement marks a significant milestone for UWA, enhancing its pivotal role in nuclear safeguards at both national and international levels! Congratulations to Matvei Aleshin and the rest of the team for this outstanding achievement!