grit42

Meet another brilliant member of the grit42 team, Mariana Ribeiro, who is working on the VICT3R project for us. Just before Christmas, Mariana released the first R package, vict3rrapi, designed to allow users in the project to connect to the grit42 API and access data without the need to interact with the grit42 platform. Mariana is a Bioinformatics and Biostatistics Master Student at School of Health Sciences - Polytechnic of Porto. She is working from Portugal at the moment but will move to Denmark to join our Copenhagen team at the beginning of February. At grit42, she will, in addition to the R package, be involved in implementing a QC/dictionary pipeline for SEND files as well as implementing the R pipeline that will generate the actual Virtual Control Groups to replace living research animals.

Planning animal studies can be a challenge. Different species, conflicting light-dark schedules, various study lengths, etc., etc. To help labs utilise their animal facilities' capacity efficiently and keep track of ongoing and future studies, we have created a new animal facility capacity module for gritAnimal. This is what one of our customers Zealand Pharma is saying: “grit42 and Zealand Pharma have, for many years, collaborated to effectively report Zealand Pharma’s animal use to the authorities. Recently, we have been able to further increase our efficiency with the addition of a new overview module that has simplified our ability to track how many rodents we have in our facilities and to plan future study capacity. Overall, we are pleased with the support, product, and collaboration we get from grit42.” - Bill Vestergaard Principal Scientist, Zealand Pharma

As the year is coming to an end, it seems like a good time for a little update on how the work with the open source version of grit is progressing. We’ve been putting considerable resources into transforming it into a modular platform, and we're happy to report that the core part is well underway. In the video below, you can get a glimpse into the platform and see how to upload data and map fields via lookup in other database tables. All that, as well as data tables with filtering options, is already in place. Right now, we are working on splitting our monolith into neatly packaged modules. The first proprietary module is also in the making. In other words, we are on track to launch the open source version in Q1, and we can’t wait to get it out there and into the hands of lab scientists and researchers.

Our CEO Claus Stie Kallesøe is one of the "Minds Behind VICT3R" - check out this interview where Claus' talks about the role grit42 plays in this important project.

Great progress on the VICT3R project! Earlier this month we were able to tick off the first delivery as we have now developed, tested, and deployed the first version of the grit42 VICT3R platform. The platform is going to contain the historical data from animal studies that researchers will use to generate virtual control groups (VCGs) in order to reduce the use of research animals and enhance accuracy and efficiency in toxicology research. Our Scientific Data Management Platform (grit) was used as the starting point for the development of the VICT3R database. We were able to re-use the general database and web platform as well as the existing frontend with data tables and the sorting, filtering, and exporting functionalities. Some of the things we have been doing so far: Updated the database model to better fit the storage of SEND data and especially to enable fast searching across large amounts of SEND data stored in several different domains. Simplified and cleaned up the entire code base so all legacy features that are not needed in the VICT3R database have been removed. Loaded data from 90.000 animals into the new database and updated the frontend dashboard to show statistics on the data and enable display, sorting, and filtering. Next up, we will start to add the underlying infrastructure for the QC/align/enrichment pipeline, which will ensure that all the control data contributed by project partners will be consistent and fit for purpose as the data source for the VCG creation.

Software selling is broken. That’s the case our CEO Claus Stie Kallesøe is making in this new blog post. The problem is that the buying and selling process in pharma too often ends up as an arm-wrestling competition between purchasing on one side and salespeople on the other - sidelining the scientific users who needed the software in the first place. That’s why we decided, that it’s a game we don’t want to play. Read more here: https://lnkd.in/dRA_GwP2

Open source version of grit in the making! Meet Jonathan REBOURT, our super-skilled developer. These days, he is kneedeep in our scientific data management platform, cleaning up code and modulising it to make it ready for re-launch as open source. We want to make it easy to download your version of grit and start using it with your own data right away, so packaging everything right and providing in-platform documentation is high on Jonathan's agenda right now. We aim to launch the open source version in Q1 - we’ll keep you updated! #grit42 #grit #opensource #rubyonrails #inthezone

This week is World AMR Awareness Week and the theme is “Educate. Advocate. Act now.” And action is very much needed. Antimicrobial resistance is a major threat to public health worldwide causing more than 1.000.000 deaths per year. This number is predicted to increase by 70% by 2050. We are proud participants in one of the programs that are taking action, AMR Accelerator. An IMI programme comprising 9 projects with the shared goal of progressing the development of new medicines to treat or prevent resistant bacterial infections. grit Scientific Data Management Platform serves as the central data store in two of these projects and in a third, the COMBINE data management project, we have helped develop FAIR data templates to ensure structured and aligned data collection across the data producers, enabling cross-study analysis.. The projects under AMR Accelerator run until 2025-2026 and right now sustainability is a hot topic. We need to ensure that research on the data can continue beyond the project period and our hope is that the upcoming open source version of grit Scientific Data Management Platform will make this easier. Innovative Health Initiative (IHI), ERA4TB

The interest in the upcoming open source version of our scientific data management platform has been overwhelming! We have been contacted by far more people than expected - from both big pharma and small research startups - who are interested in learning about the possibilities of using grit. This, of course, has to do with the fact that you can now get a "structure-aware enterprise-level data warehouse", as our long-term collaborator Dr. Phil Gribbon from Fraunhofer ITMP calls it, for free. But there’s more to the story. Read about what our CEO Claus Stie Kallesøe makes of the interest in this blog post: https://lnkd.in/dm_cfxzj

The interest in the upcoming open source version of our scientific data management platform has been overwhelming! We have been contacted by far more people than expected - from both big pharma and small research startups - who are interested in learning about the possibilities of using grit. This, of course, has to do with the fact that you can now get a "structure-aware enterprise-level data warehouse", as our long-term collaborator Dr. Phil Gribbon from Fraunhofer ITMP calls it, for free. But there’s more to the story. Read about what our CEO Claus Stie Kallesøe makes of the interest in this blog post: https://lnkd.in/dm_cfxzj