Bicycle Therapeutics

Bicycle Therapeutics

Biotechnology Research

Cambridge, England 30,198 followers

Bicycle Precision Guided Therapeutics.

About us

Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycles, for diseases that are underserved by existing therapeutics. Bicycles are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycles attractive candidates for drug development. Bicycle is evaluating BT5528, a second-generation Bicycle Toxin Conjugate (BTC™) targeting EphA2; BT8009, a second-generation BTC targeting Nectin-4, a well-validated tumor antigen; and BT7480, a Bicycle TICA™ targeting Nectin-4 and agonizing CD137, in company-sponsored Phase I/II trials. In addition, BT1718, a BTC that targets MT1-MMP, is being investigated in an ongoing Phase I/IIa clinical trial sponsored by the Cancer Research UK Centre for Drug Development. Bicycle is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA. For more information, visit bicycletherapeutics.com.

Industry
Biotechnology Research
Company size
201-500 employees
Headquarters
Cambridge, England
Type
Public Company
Founded
2009
Specialties
Drug Discovery, Phage Display, Peptide Therapeutics, and Biotechnology

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Funding

Bicycle Therapeutics 14 total rounds

Last Round

Post IPO equity

US$ 555.0M

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