BioTechniques

🎃 From the #NobelPrizes and spooky Halloween-themed news to #ELRIG Drug Discovery and #Neuroscience 2024, we had a lot of fun in October. Just in case you missed any of it, we’ve got a roundup of our favorite content pieces from the last month. 🏆 Who won the 2024 Nobel Prize in Physiology or Medicine? >>> https://lnkd.in/ecyhB3fj 🏆 Who won the 2024 Nobel Prize in Physics? >>> https://lnkd.in/e4HbEDHg 🏆 Who won the 2024 Nobel Prize in Chemistry? >>> https://lnkd.in/eQT6iAnf 🧛 Slaying vampirism in enteric bacteria >>> https://lnkd.in/eVF-GXAC 🩻 The skeleton in the well: sequencing confirms gruesome 12th-century tale >>> https://lnkd.in/e-8_jMVx 🦇 What’s spookier than bats? Fungal infections >>> https://lnkd.in/emGBuFfJ 🔎 Protein degradation in high definition >>> https://lnkd.in/emHmQKjx 🧠 Pick of the posters: Neuroscience 2024 >>> https://lnkd.in/ekiVb8_r 🍅 Are cyclic peptides the future of drug design? >>> https://lnkd.in/gjFv5FKx 🧫 Innovative assays for drug discovery and development >>> https://lnkd.in/edjpKfVK 🔊 STEM Tea | Mentoring junior faculty: how to handle the research tidal wave >>> https://lnkd.in/eWpjRcgV Plus, check out what’s happening in the journal! 📕 Latest articles >>> https://lnkd.in/evuNMHf9 📘 September issue >>> https://lnkd.in/eAZwUW-M #BTNMonthlyHighlights

Researchers from UC San Diego have developed a CRISPR-based tool that could help combat insecticide resistance but, like Mary Poppins, it disappears once the job is done. “Because insects carrying the gene cassette are penalized with a severe fitness cost, the element is rapidly eliminated from the population, lasting only as long as it takes to convert 100 percent of the insecticide-resistant forms of the target gene back to wild-type,” said first author Ankush Auradkar Rodrigo Corder, Ethan Bier https://lnkd.in/emEx-Nwa

In this episode of the STEM Tea podcast, Angela Pack joins Antentor "A.J." Hinton, Jr., Ph.D. to discuss factors to consider when pursuing a scientific career in industry as well as career options for scientists who don’t want to be at the bench.  Angela shares several tips for formulating a competitive application for industry positions and her experience as an industry professional working in vaccine development at the bench.  🔊 Listen now >>> https://lnkd.in/etJMSiCK

Find out how nanopore sequencing is addressing the challenges of metagenomics, including real-world examples of researchers applying nanopore technology to reveal unprecedented insights into microbial communities. Download for FREE now! >>> https://hubs.ly/Q02YJByw0

🗞️ Learning more about identifying and producing robust T cells for cancer immunotherapy, detecting targets of snoRNAs and why you overthink. 🗣️ Exploring  a 3D imaging methodology to quantify Parkinson’s progression in a mouse model. 🖥️ Plus, a guide from LEARN mentor Jasmine Baker on hosting your bioinformatics software on GitHub.

Learn more about the current landscape of CAR-T therapies and the future of CAR-T, including innovations, challenges and future directions in our latest Expert Interview. Read now >>> https://hubs.ly/Q02Y1R6f0

Still getting to grips with GitHub and how to upload your bioinformatics software to the platform? BioTechninques Learn Mentor Jasmine Baker, PhD, a translational and clinical bioinformatician at Baylor College of Medicine, has put together just the guide for you! With a comprehensive guide to getting set up, adding your software, managing your repository and licensing your software - including copyable code - this article should have all you need to get on your feet with the platform! https://lnkd.in/ed9j59iq

Are you an overthinker? Turns out our amygdala is in constant communication with our social cognition network, a finding that may lead to better treatments for anxiety and depression. Researchers at Northwestern University, including Rodrigo Braga and Donnisa Edmonds, used #fMRI to highlight – in high resolution – the brain network that drives our advanced ability to think about others’ potential thoughts, feelings and perspectives >>> https://lnkd.in/eaP3nHVW

🗣️ Chuan He (University of Chicago): “Once you see so many targets for these snoRNAs, you realize there’s a lot more to be understood. We already see that they play a role in protein secretion, which has major implications for physiology, and it suggests a path forward to study hundreds of other snoRNAs.” Find out how researchers have uncovered a suite of new applications for snoRNAs that could be used for the development of future drugs >>> https://lnkd.in/e-573Fg5

🧠 In this interview from #SfN24, Annie Coulson talks to Yasir Gallero-Salas at Gubra about the project, spearheaded by PhD student Frederikke Lynge Sørensen, that developed a 3D imaging methodology to quantify alpha-synuclein spreading and dopaminergic neuron loss in a mouse model of Parkinson’s disease. 🗣️ “I think our next step is to try different biologics that perhaps inhibit the spread of alpha-synuclein or other drugs that preserve the viability of the dopaminergic neurons. Because we can count all of the neurons, we have a better, unbiased and more accurate quantification of the effect of the drug.” https://lnkd.in/esVuwgjW