Harvard Pilgrim Health Care Institute

A new study led by Harvard Pilgrim Health Care Institute's Izzuddin Aris sheds light on the trajectory of cardiovascular health (CVH) early in life, which may contribute to CVH disparities in adulthood. The research team studied data from over 1,500 children from the Project Viva pre-birth cohort in eastern Massachusetts. Dr. Aris and team found that, across demographic subgroups, CVH scores begin to decline at approximately 10 years of age and appear driven by health behaviors rather than health factors. They also noted small but significant differences in CVH trajectories based on maternal socioeconomic status and child race and ethnicity. 💻 Read the study online in JAMA Cardiology: https://lnkd.in/ecR9S2JT

#DYK? Harvard Pilgrim Health Care Institute is (newly) joining the conversation over at Bluesky Social, where we hope to share news about our researchers' work and subsequent impacts on #populationhealth. https://lnkd.in/ePMQD2XV

Join us online today at 12:20pm, as Jessica Gerald Young presents, "Story-Led Causal Inference" as part of Harvard Pilgrim Health Care Institute's Research Cafe series. For more information: https://lnkd.in/dp7ww3RY About Dr. Young's work: https://lnkd.in/dddCE8kZ

A new study led by Harvard Pilgrim Health Care Institute's Izzuddin Aris sheds light on the trajectory of cardiovascular health (CVH) early in life, which may contribute to CVH disparities in adulthood. Dr. Aris, a member of the Division of Chronic Disease Research Across the Lifecourse (CoRAL), and his research team found that CVH scores start to decline around age 10 across all demographic groups, driven by health behaviors rather than health factors. They note that this decline may reflect social and/or developmental changes that typically occur at this age—such as changes in school schedules that may interfere with meeting guidelines for healthy sleep duration and/or diet—and may affect health behaviors. They suggest that improving these health behaviors, especially between mid-childhood and early adolescence, could help optimize CVH. Read the study online now in JAMA Cardiology: https://lnkd.in/ecR9S2JT

Online now in JAMA Cardiology: new work led by Harvard Pilgrim Health Care Institute's Izzuddin Aris, a faculty member in the Division of Chronic Disease Research Across the Lifecourse (CoRAL), pinpoints a pivotal period for improving cardiovascular health in children. Read more ⬇️

Funding: Diversity and Inclusion Faculty Fellowship (2025-2027)⁠ ⁠ Our two-year, non-degree fellowship provides additional support for junior faculty to conduct clinical and/or translational research, freeing them from clinical and teaching demands at a key point in their career development. Each fellow will receive $100,000 over a two-year period. ⁠ ⁠ Apply by December 13: hvrdct.me/35l ⁠ Photo: Dennis Spencer, 2021-2023 faculty fellowship awardee, in the lab.

The Sentinel Team investigated the impact of FDA regulatory actions concerning an increased cancer risk associated with HCTZ. Read the results: https://lnkd.in/e8TDnA9G

Free consulting service: NIH K Grant Specific Aims NIH K grant applicants, apply to have the specific aims section of your grant reviewed by Harvard faculty who have successfully received NIH grant funding. This service, offered by our Writing and Communication center, is available to Harvard-affiliated researchers and is currently accepting applications on a rolling basis. Learn more and apply: hvrdct.me/cx9

Joshua Petimar & Jason Block are co-authors on this study led by colleagues at Children's Hospital of Philadelphia, which assessed whether the 2017 Philadelphia beverage tax was associated with changes in pediatric weight outcomes. You can read it online now in JAMA Pediatrics:

Little is known about the frequency, hospital-level variation, predictors, and clinical outcomes of antibiotic de-escalation in suspected #sepsis. A new paper led by Kai-Qian Kam with senior author Chanu Rhee, MD, MPH, FIDSA, FSHEA of Harvard Pilgrim Health Care Institute and colleagues found that across 236 US hospitals, de-escalation of anti-MRSA and anti-pseudomonal antibiotics in suspected sepsis was infrequent and variable across hospitals. De-escalation was more common in more stable patients and associated with lower adjusted risks for kidney injury, ICU admission, and death. Read it online now in the Infectious Diseases Society of America journal, Clinical Infectious Diseases: https://lnkd.in/g-xY7jvx