HEREDITARY

🎄 Happy Holidays from the HEREDITARY Project! We are deeply grateful for the support and collaboration we've received in the first year of the project. 2024 has been incredible, yet there is still much more to come! 🔋 Now, it’s time to recharge, but we’ll be back soon to continue our journey, addressing the critical challenge of leveraging multimodal health data to improve disease prevention, diagnosis, and treatment. Merry Christmas and a Happy New Year! 🎁🎅 University of Colorado | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

🧠💉 Use Case 5: Gut-Brain Linkage and Disease Relevance. Exploring how gut microbiota influences neurodevelopmental disorders like depression, ADHD, anxiety, and autism. By combining genetic, clinical, and neuroimaging data from partnerships with international centers (Radboudumc, Università degli Studi di Padova and Università degli Studi di Torino) we use advanced deep learning to identify potential probiotic treatments based on clinical profiles. 🔍 This is the final use case to be introduced. If you missed any of them, please visit our website to find them all: https://lnkd.in/dW24QAqh #HEREDITARYProject #UseCases #GutBrainAxis #Genomics #HealthInnovation University of Colorado Boulder | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

🚀 Exciting news! The article “Toward improving reproducibility in neuroimaging deep learning studies”, done by Federico Del Pup (Università degli Studi di Padova) and Manfredo Atzori (Università degli Studi di Padova and HES-SO Valais-Wallis), has been published in Frontiers. 🎯 The paper tackles the reproducibility crisis in deep learning applications in neuroimaging, focusing on challenges like data scarcity and model generalization. It proposes a checklist of 30 key elements to improve reproducibility and promote transparency, enhancing the reliability of neuroscience research. 🔍 Check it out on our zenodo profile: https://lnkd.in/dWfQQTMm Find out the latest publications on our website: https://lnkd.in/dW7VY7H2 Stay tuned for more publications coming soon! #HEREDITARYProject #DataLearning #HealthInnovation #HealthData #Neuroscience University of Colorado Boulder | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

Use Case 4: Phenotyping of the Gut-Brain Axis in Healthy Individuals 🧠🧬 Analyzing the gut microbiota from fecal samples to understand its impact on brain structure and function. By studying deeply phenotyped healthy populations, the goal is to uncover how changes in the gut microbiome relate to conditions like diabetes, obesity, and inflammatory bowel disease.  🌍 The research also explores environmental factors that influence health outcomes, potentially revealing links between specific bacteria and brain functions or behaviors.  🔍 Want to know everything about use cases? Visit our website: https://lnkd.in/dW24QAqh #HEREDITARYProject #UseCases ##GutBrainAxis #Genomics #HealthInnovation  University of Colorado | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

📺 The UCD Mission of Observa Science in Society: Information, AI and Decision Making 📺 Here is the third and final part of our video series "The UCD Mission of Observa", where, guided by Stephen McNamara, a research instructor at the University of Colorado Anschutz Medical Campus, we delve into the potential of AI for early diagnosis of neurodegenerative diseases and ways of communicating with patients and the public. To complete this journey, Stephen addresses the key role of transparency in communicating advancements and providing information about new treatments. It’s all about giving people the whole truth, so they can evaluate whether to introduce AI in their particular cases, because it is directly affecting their lives. After all, science is for everyone and must be open to the public. 🔗 Watch the video here 👇 https://lnkd.in/dxnHUreM Don't forget to like, comment, and subscribe to stay updated with our latest videos and developments. Thank you for watching! If you missed an episode or want to rewatch it, you can do so in the Hereditary Voices section of our website 👉 https://lnkd.in/dr3-BwGw And in our latest news article with all the information about this video series 👉 https://lnkd.in/dQ5JuyKc #UCDMission #HEREDITARYProject #MedicalResearch #HealthData #AIdiagnosis #neurodegenerativediseases University of Colorado Boulder | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

Use Case 3: Signs of Parkinson’s Disease in Multimodal Data 🧠👀 Exploring Parkinson's and related diseases through ocular imaging and brain biomarkers. Using advanced technologies like OCT, MRI, PET, and neurophysiology to identify patterns and predict disease progression. With deep learning and predictive models, we aim to uncover new ways to identify and classify patients, exploring the connection between ocular and brain biomarkers. 💡 🔍 Explore our website to learn more about Uses Cases: https://lnkd.in/dW24QAqh #HEREDITARYProject #UseCases #DataIntegration #MultimodalData #HealthInnovation #ParkinsonDisease University of Colorado | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

📺 The UCD Mission of Observa Science in Society: The Eye. The mirror of the body 📺  Here is the second part of our video series "The UCD Mission of Observa", where, guided by Stephen McNamara, a research instructor at the University of Colorado Anschutz Medical Campus, we delve into the potential of AI for early diagnosis of neurodegenerative diseases and ways of communicating with patients and the public.  This time, Stephen tells us about the eye's potential to make diagnoses and establish connections between the whole body. This improves the quality of life for patients, increasing certainty about different diseases, as well as establishing specific therapies and treatments instead of jumping from one specialist to another. Stay tuned for the last episode on the following week! 🔗 Watch the video here 👇  https://lnkd.in/ey9sGUtA Don't forget to like, comment, and subscribe to stay updated with our latest videos and developments. Thank you for watching! #UCDMission #HEREDITARYProject #MedicalResearch #HealthData #AIdiagnosis #neurodegenerativediseases University of Colorado | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

💡 Use Case 2: Next-Generation Diagnosis and Treatment Response for Neurodegenerative Diseases. 🧠 By integrating clinical, imaging, genetic, and environmental data, we're using AI to identify patient clusters and optimize treatments. We seek to personalize care and improve quality of life, understanding disease progression and environmental factors. This second use case focuses on Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS) and Frontotemporal Dementia (FTD) with the collaboration from Università degli Studi di Torino, Università degli Studi di Padova, Centre for Genomic Regulation (CRG), and public/open data. 🌍 🔗 Dive in and discover more on our website: https://lnkd.in/dW24QAqh #HEREDITARYProject #UseCases #DataIntegration #Genomics #HealthInnovation University of Colorado | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

📺 The UCD Mission of Observa Science in Society: Clinical tools for diagnosis 📺  We are thrilled to present the first part of our new video series "The UCD Mission of Observa", where, guided by Stephen McNamara, a research instructor at the University of Colorado Anschutz Medical Campus, we delve into the potential of AI for early diagnosis of neurodegenerative diseases and ways of communicating with patients and the public.  On this occasion, Stephen explains how ocular biomarkers can help to determine whether someone has a neurodegenerative disease, such as Parkinson, now or in the near future. Like that, we can avoid invasive imaging or testing for patients. More insights to come in the following weeks! Stay tuned! 🔗 Watch the video here 👇  https://lnkd.in/dZuesZzb Don't forget to like, comment, and subscribe to stay updated with our latest videos and developments. Thank you for watching! #UCDMission #HEREDITARYProject #MedicalResearch #HealthData #AIdiagnosis #neurodegenerativediseases University of Colorado | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven

#ThrowbackTime to the IEEE VIS Conference 2024 where our partner Technische Universität Graz presented the award-winning poster DROPLETS: A Marker Design for visually enhancing Local Cluster Associations on Sunday 13th October as part of a submission to the Bio+MedVis Challenge. ✨ It was presented by Stefan Lengauer, who is one of the authors alongside Peter Waldert and Tobias Schreck. Dropplets serve as a space-saving design for visually enhancing the presence of clusters and regional borders, giving response to the Bio+MedVis Challenge objective. 💡 The poster received an award for the novelty and innovative Visualization technique design. 🏆 Check out the summary poster, the full publication and more details on our website! 🌐 🔗 https://lnkd.in/dzuxrBce #HEREDITARYProject #IEEEVIS2024 #AwardWinningPoster University of Colorado | Aalborg Universitet | Università degli Studi di Padova | Radboudumc | Ontotext | HES-SO Valais-Wallis | Universidade Nova de Lisboa | European Bioinformatics Institute | EMBL-EBI | Technische Universität Graz | SURF | Università degli Studi di Torino | Centre for Genomic Regulation (CRG) | Centro Nacional de Análisis Genómico (CNAG) | FEUGA. Fundación Empresa Universidad Gallega | European Brain Council | Observa Science in Society | European Genome-phenome Archive (EGA) | EUpALS | KU Leuven