Journal Biology of the Cell

The French Societies for Cell Biology and Developmental Biology, as well as CNRS and INSERM, are joining forces to co-organize the conference “From Cells to Organism: When Cell Biology Meets Development” in Paris from October 16 to 19, 2024. https://lnkd.in/e2-84Kpx

Meet our editorial board members: An interview with Tsuyoshi Hirashima, National University of Singapore. https://lnkd.in/eDp3q_DD

Mylan Ansel, Kaustubh Ramachandran, Gautam Dey, Thibaut Brunet published in Journal Biology of the Cell: "Origin and evolution of microvilli". https://lnkd.in/eYu9w_GT

Ghaleno LR et al published in Journal Biology of the Cell: "While the HA-Alg composite did not support spermatogenesis in the 3D culture of mouse testicular cells, it demonstrated an unpredicted potential for promoting the differentiation of neonate mouse testicular cells into HLC, erythrocytes, and other cell lineages." https://lnkd.in/eNzRAF6y

Bucchi C et al published in Journal Biology of the Cell: "The results show that the traditional method produces irregular and not straight gaps, and had the worst cell migration rates compared to the other groups. The wounding tool produced scrape signs at the well surface." https://lnkd.in/eTsHtWYD

Simanov G et al new publication in Journal Biology of the Cell: "Here we analyzed expression levels of Arpin and various markers using Reverse Phase Protein Array (RPPA) in human mammary carcinomas. We found that Arpin protein levels were correlated with those of several DNA damage response markers. Arpin-null cells display enhanced clustering of double stand breaks (DSBs) when cells are treated with a DNA damaging agent, in line with a previously described role of the Arp2/3 complex in promoting DSB clustering for homologous DNA repair (HDR) in the nucleus. Using a specific HDR assay, we further showed that Arpin depletion increased HDR efficiency two-fold through its ability to inactivate the Arp2/3 complex." Alexis Gautreau https://lnkd.in/ebdPVUZz

Zhu H et al published their results in BoC! "In concert with recently characterized MIPs, our in situ observations within a living organism corroborate the hypothesis that intricate luminal assemblages exist within microtubule scaffolds. These findings necessitate further exploration into the molecular constituents and functional ramifications of these internal microtubular configurations in both cellular physiology and pathophysiology." https://lnkd.in/e6bwXF7J

Sharma A et al published an article: "LncRNA HULC augments high glucose-associated pancreatic cancer progression and drug resistance by enhancing YAP activity and autophagy" Inhibition of lncRNA highly upregulated in liver cancer (HULC) and YAP may represent a novel therapeutic strategy for pancreatic ductal adenocarcinoma cells (PDAC). Furthermore, this study portrays the intricate molecular interplay between HULC, YAP and autophagy in PDAC pathogenesis. https://lnkd.in/gT-BcFdm

Li M et al published an article: "FOXM1 transcriptional regulation". They review the role of FOXM1 in the formation and development of malignant tumors, and they provide a comprehensive summary of the role of FOXM1 in transcriptional regulation, interacting proteins, tumor microenvironment, epigenetics, and immune infiltration, and suggest areas for further research. https://lnkd.in/gPXQMcDC

Call for Papers!! "Intracellular trafficking in physiopathology" Submission deadline: Monday, 30 September 2024 https://lnkd.in/ga79mfgK