GERLI Association’s Post

𝑴𝒂𝒓𝒌 𝒀𝒐𝒖𝒓 𝑪𝒂𝒍𝒆𝒏𝒅𝒂𝒓𝒔! You are all invited to attend the aforementioned talk on Friday, 2nd August 2024, from 10:00 a.m to 11:00 a.m in the Assembly Hall. For more information, please see the poster below. #technicaluniversityofmombasa #publichealthsurveillance #metagenomics #infectiousdiseases #nextgensequencing

📍 Benchmarking algorithms for single-cell multi-omics prediction and integration Hu et al. presented a benchmark study of 14 protein abundance/chromatin accessibility prediction algorithms and 18 single-cell multi-omics integration algorithms using 47 single-cell multi-omics datasets. Key points ◼ totalVI and scArches outperforming the other algorithms for predicting protein abundance ◼ LS_Lab as the top-performing algorithm for the prediction of chromatin accessibility in most cases ◼ Seurat, MOJITOO and scAI emerge as leading algorithms for vertical integration ◼ totalVI and UINMF as leading algorithms in both horizontal and mosaic integration scenarios Apipeline to assist researchers in selecting the optimal multi-omics prediction and integration algorithm. ➡ More details: https://lnkd.in/ecRPSvS9 #UniversityofScienceandTechnologyofChina #USTC #spatialomics #spatialbiology #singlecellanalysis #singlecell

Identify potentially 1000s of proteins in pathological #TissueSamples and explore their molecular function. Hear what the latest tech from Molecular Machines and Industries AG can do in the latest episode of #ListenIn. #TissueBiology #SpatialBiology Access here → https://buff.ly/3yq4rOX

We recently had the opportunity to chat with Dr. Kanstantsin Siniuk, PhD, from the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Germany, about his collaboration with Cytosurge on a pivotal project. Dr. Siniuk needed a precisely edited U2OS cell line, and he turned to our #CellEDIT Service to achieve his research goals. 🧬🤩   In our full Q&A, Dr. Siniuk shares his experience with the CellEDIT Service, detailing how it played a crucial role in finalizing his project and submitting his paper for review. He discusses the specific genetic modifications made to the #U2OS cell line, the efficiency and precision of the editing process, and the smooth, productive collaboration that ensured the success of his research 👉 https://lnkd.in/gUksDBqN                                                                                                                     💥 Configure your U2OS cell line and take advantage of our summer sale 🎁🎉 (until the end of September) 👉 https://lnkd.in/g3XBu5x9   #CellEngineering #GeneEditing #singlecell #Research #CRISPR #Innovation #team #connection #FluidFM #CellBiology #CellEngineering #GeneEditing #Biotech #ResearchInnovation  #Scientist #ScienceAsAService #Sales #Discount

🚀 Next in our technology spotlight series: miR-eCLIP! 🚀 miR-eCLIP provides direct mapping of miRNA-mRNA and siRNA-mRNA interactions, offering deep insights into the biology of miRNAs and the detection of siRNA off-targets. Why Choose miR-eCLIP? • Discover miRNA Biology: Determine exactly where and how miRNAs bind, revealing the entire network of miRNA activity. • Find siRNA Off-Targets: Locate off-target binding by siRNAs to improve drug design. • Design Better AMOs: Improve miRNA blockers by identifying the specific bases involved in binding Swipe below to see how miR-eCLIP can enhance your research and drug development programs and visit our website to learn more: https://lnkd.in/g4Rjyt8a #TechnologySpotlight #RNAresearch #miReCLIP #miRNA #siRNA #Eclipsebio

While great to be here at the 74th annual meeting of the American Crystallographic Association (ACA) in Denver, it is with pride and humility to realize that of the 74 years of the existence of the ACA meetings, our expertise, experience and presentations have gone into about 30% (25 years) of that time: (1) 10 years of delivering protein X-ray crystallography-driven drug discovery in our ABS-Services and ABS-OneStep platforms and services (www.accelerobio.com) to drug discovery and biopharma/biotech companies, and which is built on (2) 15 years of building and deploying high-throughput structural biology and structural genomics at the JCSG (Joint Center for Structural Genomics) & BSGC (Berkeley Structural Genomics Center). It is noteworthy that our work in structural genomics on “Exploration of Uncharted Regions of the Protein Universe” led to being the “largest contributor of novel structural leverage”, which led to ~1500 novel experimentally-determined protein crystal structures from JCSG deposited in the Protein Data Bank (PDB), and ~300 publications, which ultimately contributed to recent new advances in protein structure prediction methods (as well as earlier methods) involving ML/AI (AlphaFold, etc). This is captured in a new slide made today as part of our oral presentation at the ACA conference tomorrow. #structuralbiology #drugdiscovery

Identify potentially 1000s of proteins in pathological #TissueSamples and explore their molecular function 🤓 See what the latest tech from MMI - Molecular Machines & Industries can do in our latest webinar. Watch now → https://buff.ly/4buLd9J #TissueBiology #SpatialBiology

What if you could ‘glue’ spatial and molecular data seamlessly? SpatialGlue, a newly developed model, does just that, providing a cohesive understanding of tissue complexity. Learn how to integrate multimodal data with precision with SpatialGlue in today’s blog: https://lnkd.in/e3gU5mqX #MultiOmics #SpatialOmics #Bioinformatics #LifeSciences #DataIntegration

If our data resources have ever saved you 10 minutes, here’s your chance to give back. Help us shape the future data resources managed by EMBL-EBI and collaborators. Share your experience in this short 8-minute survey. Tell us about what resources you use and how, what impact they have on your work, and how they can be improved.   🗓️ The survey is open until 7 June, and we welcome responses from all over the world, regardless of usage level. https://lnkd.in/eEPJ5RMf #bioinformatics #FAIRdata #opendata #computationalbiology Ensembl European Genome-phenome Archive (EGA) European Nucleotide Archive GWAS Catalog InterPro/Pfam Protein Data Bank in Europe (PDBe) CancerModels.Org

Did you know, in 2010, scientists at the J. Craig Venter Institute created the first synthetic bacterial cell, named Mycoplasma mycoides JCVI-syn1.0. This organism's entire genetic material was synthesized from chemicals, marking the first instance of creating "life" wholly controlled by man-made genetic instructions. This breakthrough not only advanced our understanding of the fundamental principles of life but also sparked a profound ethical and philosophical debate about the nature and future of synthetic biology. The creation of this synthetic cell is a prime example of the innovation that defines global laboratories. This milestone not only expanded our knowledge of life’s blueprint but also illustrated the broader scope of laboratory impacts—from groundbreaking research to vital diagnostics. On World Lab Day, we celebrate not just these innovations but also the everyday contributions of diagnostic laboratories. These facilities are essential for the timely diagnosis and management of diseases, enabling healthcare providers to deliver precise treatments based on early detection. Biorus is committed to supporting these efforts by providing top-quality solutions that enhance laboratory research and diagnostics, ensuring accurate and timely results for better patient care. #worldlabday2024 #WLD24 #diagnostics #innovation #facttuesday #factasticbybiorus #biorus