𝙃𝙤𝙬 𝙩𝙤 𝙢𝙖𝙞𝙣𝙩𝙖𝙞𝙣 𝙨𝙩𝙚𝙢 𝙘𝙚𝙡𝙡 𝙘𝙪𝙡𝙩𝙪𝙧𝙚𝙨 𝙢𝙤𝙧𝙚 𝙚𝙛𝙛𝙞𝙘𝙞𝙚𝙣𝙩𝙡𝙮 𝙖𝙣𝙙 𝙝𝙤𝙢𝙤𝙜𝙚𝙣𝙚𝙤𝙪𝙨𝙡𝙮? #Stemcell maintenance requires the proper activation of FGF signalling, as the growth factor FGF-2 is involved in a variety of biological processes, including embryonic development, neural differentiation, and the proliferation of cells of mesodermal origin 🧬 👉 Therefore, the addition of exogenous FGF-2 is required to sustain stem cell self-renewal, and their capacity to differentiate into a large number of somatic cell types. Still, the application of commonly commercialized FGF-2 is limited due to its rapid loss during cultivation, as extensive research studies have shown FGF-2 to be unstable at physiological conditions, with a half-life of approximately 8 h in mammalian cell culture 🧫 As such, the need for a FGF-2 product with excellent stability is essential -specially as the field of stem cell research and manufacturing continues moving towards serum-free / chemically defined cell culture media conditions 🧪 Core Biogenesis is pleased to provide one of the most advanced options in the market to integrate a highly stable FGF-2 molecule to achieve #consistency during #StemCellCultures. Our star product 𝗙𝗚𝗙-𝟮 𝗧𝗢𝗣® (𝗧𝗵𝗲𝗿𝗺𝗼𝘀𝘁𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗢𝗽𝘁𝗶𝗺𝗶𝘇𝗲𝗱), is available to satisfy all the demands and needs from the research to the clinical manufacturing stages, now being also developed in #GMPgrade in collaboration with our partner, Nucleus Biologics. ⏩ Scroll to have a glimpse of the amazing attributes and performance of FGF-2 TOP® (𝘛𝘩𝘦𝘳𝘮𝘰𝘴𝘵𝘢𝘣𝘪𝘭𝘪𝘵𝘺 𝘖𝘱𝘵𝘪𝘮𝘪𝘻𝘦𝘥) 𝚈𝚘𝚞 𝚌𝚊𝚗 𝚕𝚎𝚝 𝚞𝚜 𝚔𝚗𝚘𝚠 𝚢𝚘𝚞𝚛 𝚒𝚗𝚝𝚎𝚛𝚎𝚜𝚝 𝚏𝚘𝚛 𝚎𝚟𝚊𝚕𝚞𝚊𝚝𝚒𝚘𝚗 𝚊𝚝 𝚢𝚘𝚞𝚛 𝚍𝚎𝚜𝚒𝚛𝚎𝚍 𝚐𝚛𝚊𝚍𝚎 𝚋𝚢 𝚌𝚘𝚗𝚝𝚊𝚌𝚝 𝚞𝚜 𝚑𝚎𝚛𝚎: https://lnkd.in/eXTG3S8h #StemCells #Research #CellTherapy #GrowthFactors #SustainableSciene
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New application note 'Stability of Qkine recombinant growth factors and cytokines in conditioned media ' testing Qkine high purity and bioactivity growth factors. FGF-2 is a key component of stem cell media, well known to be unstable under cell culture conditions, leading to the necessity for daily media changes to maintain culture conditions for stem cell culture. Although the thermo-instability of FGF-2 is well documented, the thermostability of other essential growth factors has not been investigated. This application note reviews the stability of Qkine growth factors under cell culture-like conditions to ensure maximum cost effectiveness and reproducibility in stem cell cultures. View application note > https://zurl.co/2YU6 Growth factors tested in this application note GM-CSF (Qk076) > https://zurl.co/jIdG IL-6 (Qk093) > https://zurl.co/DoQ7 IGF-1 (Qk047) > https://zurl.co/v776 IGF-1 LR3 (Qk041) > https://zurl.co/RECq GDNF (Qk051) > https://zurl.co/2Xa0 BMP-4 (Qk038) > https://zurl.co/IVmQ HGF-NK1 (Qk013) > https://zurl.co/oL6q TGF-β1 PLUS (Qk010) > https://zurl.co/Ef0c #growthfactors #stemcells #research #proteins
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New application note 'Stability of Qkine recombinant growth factors and cytokines in conditioned media ' testing Qkine high purity and bioactivity growth factors. FGF-2 is a key component of stem cell media, well known to be unstable under cell culture conditions, leading to the necessity for daily media changes to maintain culture conditions for stem cell culture. Although the thermo-instability of FGF-2 is well documented, the thermostability of other essential growth factors has not been investigated. This application note reviews the stability of Qkine growth factors under cell culture-like conditions to ensure maximum cost effectiveness and reproducibility in stem cell cultures. View application note > https://zurl.co/2YU6 Growth factors tested in this application note GM-CSF (Qk076) > https://zurl.co/jIdG IL-6 (Qk093) > https://zurl.co/DoQ7 IGF-1 (Qk047) > https://zurl.co/v776 IGF-1 LR3 (Qk041) > https://zurl.co/RECq GDNF (Qk051) > https://zurl.co/2Xa0 BMP-4 (Qk038) > https://zurl.co/IVmQ HGF-NK1 (Qk013) > https://zurl.co/oL6q TGF-β1 PLUS (Qk010) > https://zurl.co/Ef0c #growthfactors #stemcells #research #proteins
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Mesenchymal Stem Cells (MSCs): Definitions, Nomenclature, and Terms - https://lnkd.in/g_jTFXUk To analyze the emerging global market for mesenchymal stem cells (MSCs), it is important to define the cell type. Broadly defined, MSCs are multi-potent stem cells that can differentiate into a diverse range of cell types. More specifically, MSCs are non-hematopoietic stromal cells that are capable of differentiating into, and assisting in the repair of, tissues of both intra-mesenchymal and extra-mesenchymal lineages. Interestingly, MSCs exert their therapeutic effects primarily through paracrine signaling, a process where they secrete bioactive molecules such as cytokines, growth factors, and extracellular vesicles to influence nearby cells and tissues, rather than through direct differentiation into the specific target cells they aim to support or repair. Today, there is controversy over what constitutes a “true” mesenchymal stem cell or MSC. Debate also exists as to what is the best and most accurate terminology to be used for naming purposes. This has resulted in the existence of alternative nomenclature for the cell type, which include: Mesenchymal Stem Cell Marrow Stromal Cell Multipotent Stromal Cell Colony-Forming Unit-fibroblasts (CFU-f) Medicinal Signaling Cell What other names would you add to this list? #msc #stemcell #research
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🗣️ Peer stem cell scientists 🥼 Your work from #stemcell research to #celltherapy development is changing the world of human biology and medicine 🔬 To uncover all the potential of your stem cell cultures, your 𝒊𝒏 𝒗𝒊𝒕𝒓𝒐 experiments need to be representative of the 𝒊𝒏 𝒗𝒊𝒗𝒐 effects. As such, you deserve the technologies and tools that bring you a perfect balance between accurate cell signalling, and optimized cell culture conditions 🧫 ⚡️ This is FGF-2 TOP®, the thermostable version of FGF-2 (bFGF) that enables to get your desired cell response at all times: https://lnkd.in/eWz3-qHW ➡ To keep 100% of pluripotency ➡ To improve stem cell expansion into large culture vessels ➡ To ensure consistent phenotypes during your differentiation workflows 🏅 In sum, a TOP performing growth factor for your high quality stem cell cultures. After collaborating with hundreds of scientist around the world 🌍 to optimize their culture protocols, this thermostable FGF-2 is now also developed in GMP grade, in collaboration with our partner, Nucleus Biologics. Want to use it? We have 2 special offers for you 🙌 For the RUO Grade: Core Biogenesis will duplicate the amount you get (available for both formats 50µg and 1mg): If you get 50µg, we provide 100µg; If you get 1mg, we provide 2mg; If you get 50mg, we provide 100mg! For the GMP Grade: you can get first access here: https://lnkd.in/eXTG3S8h Only until the end of the year! To submit your interest, request a quote or product quantity, our team will help you at: customers@corebiogenesis.com 💚 #StemCellResearch #CellTherapy
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iPSC Generation Services ✨ From healthy or disease tissue samples, our team of stem cell experts can safely and efficiently generate your iPSCs in 2-3 months using optimized protocols. For over 15 years, we've completed various projects using unique reprogramming methods, from episomal to retroviral. - High reprogramming efficiency (>95% success rate) - iPSC generation from various donor cell types - Integration-free (episomal/mRNA/viral-based) or retroviral reprogramming - iPSCs characterized for morphology and pluripotency markers - Fast Turnaround: 2-3 months - GMP iPSC Generation Available We understand that iPSC reprogramming can be a complex and time-consuming process. That's why our team is dedicated to supporting your iPSC projects from start to finish. We can deliver your iPSCs with a complete characterization report or support your downstream research with custom iPSC genome editing and differentiation. Learn more @ 🔗 https://lnkd.in/gRKQz7CN or contact us at info@appliedstemcell.com #iPSC #ipscgeneration #celltherapy #drugdiscovery #diseasemodeling
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The global stem cells market is expected to grow at a robust rate of 9-12% for Forecasts 2023 to 2028. To learn more: https://lnkd.in/dJBKrb-h 🚀 This growth is driven by several factors: 🔹 Increasing prevalence of chronic diseases 🏥 🔹 Surge in research activities and favorable government support 🧬 🔹 Expanding clinical applications in regenerative medicine 🌿 🔹 Technological advancements in stem cell therapies 🔬 #StemCells #RegenerativeMedicine #Biotechnology #HealthTech #MedicalDevices #FutureOfHealthcare #Genomics #BioPharma
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🚀 Exciting Developments in the Mesenchymal Stem Cells (MSC) Market! The MSC market is witnessing remarkable growth, increasing from $3.00 billion in 2023 to $3.38 billion in 2024, with a 12.5% CAGR. Projections show the market reaching $5.45 billion by 2028 with a 12.7% CAGR. Key drivers of this growth include: 🌟 A paradigm shift towards regenerative medicine 🤝 Collaborative research efforts 📣 Increased public awareness and patient advocacy 🌐 International collaboration and standardization Looking ahead, the future of the MSC market is promising, driven by: 🧬 Advances in genetic engineering and personalized medicine 🤖 Integration of AI and data analytics 🧩 Innovations in biomaterials and 3D bioprinting 🧪 Development of microfluidic devices and organ-on-a-chip models ⚙️ Adoption of next-generation manufacturing technologies Additionally, major trends such as bioprinting, gene editing, expanded clinical applications, combination therapies, and the study of MSC-derived extracellular vesicles are gaining traction. As the largest market, North America is leading the way, while Asia-Pacific is the fastest-growing region. With ongoing advancements and strategic investments, the MSC market is poised for significant growth. 🔗 For a detailed report, visit: Mesenchymal Stem Cells Market Report 2024 https://lnkd.in/gcBzFgnq
Key Trends And Drivers In The Mesenchymal Stem Cells Market 2024
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The stem cell therapy market for osteoarthritis is rapidly evolving, with several key players driving innovation and growth. Here's a brief look at the leaders shaping this promising field: 🔬 Medipost - Pioneering advanced stem cell treatments with a focus on regenerative medicine, Medipost is enhancing osteoarthritis management through cutting-edge technologies. #Medipost #StemCellTherapy 🔬 Nature Cell - Specializing in cellular therapies, Nature Cell is making strides in developing effective stem cell solutions for osteoarthritis, aiming to improve patient outcomes. #NatureCell #Osteoarthritis 🔬 Theracell Advanced Biotechnology - With a robust portfolio of regenerative therapies, Theracell is at the forefront of stem cell innovation, offering novel treatments for osteoarthritis. #Theracell #AdvancedBiotechnology 🔬 Takeda (TiGenix) - Through its acquisition of TiGenix, Takeda is leveraging advanced stem cell research to advance osteoarthritis therapies, focusing on transformative solutions for patients. #Takeda #TiGenix #HealthcareInnovation #RegenerativeMedicine #Biotech #MedicalResearch #ClinicalTrials #PatientCare #Pharma #Biotechnology #HealthTech #FutureOfMedicine #StemCellTherapy #OsteoarthritisTreatment #RegenerativeMedicine #StemCellResearch #Osteoarthritis #CellularTherapy #MedicalInnovation #Healthcare #Biotech #Pharmaceuticals Read Report @ https://lnkd.in/gzKkt8Zs
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Stem Cell Assays Market worth $4.5 billion by 2027 Download PDF Brochure:-https://lnkd.in/dk6JThJu The size of global stem cell assays market in terms of revenue was estimated to be worth USD 1.9 billion in 2022 and is poised to reach USD 4.5 billion by 2027, growing at a CAGR of 17.7% from 2022 to 2027. Global Stem Cell Assays Market Dynamics -Driver: Increasing funding for stem cell research -Restraint: Issues in embryonic stem cell research -Opportunity: Government initiatives to boost stem cell research -Challenge: Dearth of trained and skilled professionals North America was the largest regional market for Stem cell assays market in 2021. 𝐓𝐡𝐞 𝐜𝐨𝐦𝐩𝐚𝐧𝐢𝐞𝐬 𝐟𝐞𝐚𝐭𝐮𝐫𝐞𝐝 𝐢𝐧 𝐭𝐡𝐢𝐬 𝐫𝐞𝐩𝐨𝐫𝐭 𝐢𝐧𝐜𝐥𝐮𝐝𝐞 Thermo Fisher Scientific Merck KGaA, Darmstadt, Germany Danaher Corporation Becton, Dickinson and Company Bio-Rad Laboratories PerkinElmer Agilent Technologies Promega Corporation CELL BIOLABS, INC. Miltenyi Biotec STEMCELL Technologies Bio-Techne FUJIFILM Holdings Corporation Charles River Laboratories HemoGenix, Inc Lonza Takara Bio Inc. Creative Bioarray AAT Bioquest, BPS Bioscience Inc., Enzo Biochem Inc PromoCell Biotium Geno'Era Technology abcam ReachBio undefined #stemcellassays #stemcellresearch #cellassays #stemcellbiology #stemcelltech
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🌟 𝐑𝐚𝐩𝐢𝐝 𝐆𝐫𝐨𝐰𝐭𝐡 𝐢𝐧 𝐭𝐡𝐞 𝐒𝐭𝐞𝐦 𝐂𝐞𝐥𝐥 𝐌𝐚𝐧𝐮𝐟𝐚𝐜𝐭𝐮𝐫𝐢𝐧𝐠 𝐌𝐚𝐫𝐤𝐞𝐭! 🌟 𝐂𝐥𝐢𝐜𝐤 𝐇𝐞𝐫𝐞, 𝐓𝐨 𝐆𝐞𝐭 𝐅𝐫𝐞𝐞 𝐒𝐚𝐦𝐩𝐥𝐞 𝐑𝐞𝐩𝐨𝐫𝐭 https://lnkd.in/gaH3djRy The stem cell manufacturing market is experiencing remarkable expansion, driven by advancements in regenerative medicine, increasing clinical research, and the growing demand for effective treatments for a range of diseases. Stem cells have the unique ability to develop into different cell types, offering immense potential for treating conditions such as cancer, neurodegenerative diseases, and cardiovascular disorders. 🔍 Key Market Drivers: Advancements in Regenerative Medicine: Innovations in stem cell technology and regenerative therapies are driving the demand for high-quality stem cell manufacturing. Increasing Clinical Research: The growing number of clinical trials and research studies exploring the therapeutic potential of stem cells is boosting the need for scalable and reliable manufacturing processes. Rising Demand for Personalized Medicine: The shift towards personalized medicine, where treatments are tailored to individual patients, is fueling the growth of the stem cell manufacturing market. 📊 Market Trends: Automated Manufacturing Processes: The adoption of automated and scalable manufacturing technologies is enhancing the efficiency, consistency, and scalability of stem cell production, reducing costs and time-to-market. Development of GMP Facilities: The establishment of Good Manufacturing Practice (GMP) facilities is ensuring the production of stem cells that meet rigorous quality and regulatory standards, crucial for clinical applications. Expansion of Allogeneic Stem Cell Therapies: The development of off-the-shelf allogeneic stem cell therapies, which use donor stem cells, is increasing due to their potential for broader application and immediate availability. #Company Thermo Fisher Scientific Merck Group BD Bio-Rad Laboratories Miltenyi Biotec Takara Bio USA, Inc. STEMCELL Technologies Pharmicell Co.,Ltd. Anterogen Cellular Dynamics Medipost Lonza Holostem S.r.l. Pluristem #Type Product Services #Application Pharmaceutical and Biotechnology Companies Cell Banks and Tissue Banks Others #StemCellManufacturing #RegenerativeMedicine #HealthcareInnovation #Biotechnology #ClinicalResearch #MarketTrends #GMPFacilities #AutomatedManufacturing #AllogeneicTherapies #PersonalizedMedicine #MedicalAdvancements #StemCellTherapies #HealthcareAdvancements #FutureOfHealthcare #CellTherapy #Biopharmaceuticals #MedicalResearch #PatientCare #StemCellTechnology #InnovationInHealthcare
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