Jeroen Elassaiss-Schaap’s Post

You may have heard of imaging flow cytometry, but how much do you know about it, and how can you elevate your cell research with it? Bring all your burning questions about cell analysis to this upcoming webinar brought to you by BD Biosciences where Raffaello Cimbro from AstraZeneca will delve into the ins and outs of advanced imaging flow cytometry and how it can help you tackle previously unanswerable biological questions. #AD Register now: https://ow.ly/HsY050RKn83

🔍 Wondering why preclinical imaging should be on your radar? This video breaks it down for you!   • Invaluable Insights: Preclinical imaging supports many research fields by providing new and integrated in vivo insights. • Non-invasive and longitudinal monitoring: Fully compliant with the 3Rs principles, allowing researchers to study disease in real-time quantitatively at a molecular level. • Monitor Progress: Repeatedly and non-invasively monitor disease onset, progression, and treatment response.   With the CUBES, you can benefit from scalable, compact, and intuitive imaging solutions with the highest performance supported by fast and simple workflows. Our state-of-the-art modular benchtop solutions make molecular imaging more accessible to a broader community of researchers in preclinical drug discovery, development, and fundamental and translational research.   👉 Ready to elevate your research game? Visit our website to learn more! Or visit us at #EANM24 in Hamburg from 19 until 23 October, Hall H booth H10.   #MolecularImaging #PreclinicalImaging #PreclinicalResearch

𝐒𝐢𝐫𝐢𝐮𝐬𝐗𝐓 𝐚𝐧𝐝 𝐜𝐨𝐥𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐬 𝐩𝐫𝐞𝐬𝐞𝐧𝐭 𝐭𝐡𝐞 𝐒𝐗𝐓-100 𝐒𝐨𝐟𝐭 𝐗-𝐫𝐚𝐲 𝐌𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞 𝐚𝐭 𝐄𝐌𝐂2024 - 𝐛𝐫𝐢𝐧𝐠𝐢𝐧𝐠 𝐭𝐡𝐞 𝐩𝐨𝐰𝐞𝐫 𝐨𝐟 𝐭𝐡𝐞 𝐬𝐲𝐧𝐜𝐡𝐫𝐨𝐭𝐫𝐨𝐧 𝐭𝐨 𝐭𝐡𝐞 𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲!🔬 The image below shows Dr. Johannes Groen, Institut Pasteur, Paris, presenting results of trials to integrate Soft X-ray Tomography (SXT) into correlative imaging workflows. The goal is to demonstrate that faster and more accurate targeting of regions of interest in a cell, using SXT, leads to more efficient and higher-throughput imaging workflows and, ultimately, accelerates the understanding of disease mechanisms and the development of new vaccines and therapeutics! 💻To learn more about Soft X-ray Tomography visit https://bit.ly/3S5LoAa ✉or email us at: info@siriusxt.com #emc2024 #Innovation #SXT #Laboratory #Synchrotron #Science #Research #Microscopy #Microscope #Copenhagen #Denmark #EU #STEM #Networking #Conference #Event #SiriusXT #SXT #Biotech #Biology #Imaging #Presentation #Paris #Collaboration #Vaccines

1. Researchers from the University of Cincinnati developed a new method to accelerate drug discovery, aiming to shorten the timeline from years to months. 2. The study was published in Science Advances on August 30. 3. The method combines data from the LINCS database and targeted docking simulations to identify potential drugs. 4. This approach significantly reduces screening time from weeks to just an afternoon. 5. The new method is not only faster but also more efficient in identifying effective compounds. 6. It offers hope for treatments of diseases with no known cures, including cancer. 7. The accelerated process could enhance responses to public health crises, like the COVID-19 pandemic. 8. The study emphasizes the potential for more targeted treatment options in precision medicine.

Another successful AACR in the books for Teiko! Great energy from scientists, clinicians, advocates, and patients, with tons of promising science on display. It's clear that understanding the fuller picture is key in drug development. Pharma companies are increasingly interested in diving deeper into the mechanisms behind their drugs, particularly the biological changes and the unique dynamics of the immune system, that drive treatment response in patients. We're seeing a surge in interest for high-dimensional approaches like mass cytometry, full spectral flow cytometry, and spatial proteomics of blood and tumor samples. It's not one or the other, but a suite of complementary and validating assays that provide valuable insights to accelerate drug development, approval, and treatment access to patients. 💪 #AACR #AACR24 #Science #DrugDiscovery #MassCytometry #FlowCytometry #Innovation #PrecisionMedicine #Immunotherapy

In this short movie, you can see the mechanical effect/ stress on the cellular and the intracellular levels in diagnostic and especially in treatment applications. I invite you to watch. 🎤Presenter: Professor Ayache Bouakaz ⏱️In Scientific session Non-ionising radiation: Ultrasound-mediated drug delivery Title: Recent advances in ultrasound-mediated drug delivery: Insights from preclinical and clinical trials. #UltrasoundMechanics #CellularStress #IntracellularEffects #DiagnosticApplications #TreatmentApplications #ScientificSession #NonIonisingRadiation #UltrasoundDrugDelivery #ClinicalTrials #PreclinicalResearch

✳ We are thrilled to share our exclusive interview with the amazing Professor Don Ingber, founding director of the Wyss Institute at Harvard University and pioneer of the organs-on-chip #OoC technology. 🔵 Among the highlights of the interview, Prof. Ingber discussed the success of Emulate, Inc.'s Liver-chips in predicting drug-induced liver injury (#DILI), bone marrow chips and their potential to assess drug side effects and contribute to personalized medicine and the reasons that make #OoC technology a “revolutionary approach to better understand human diseases and assess drug toxicity.” 🔴 The researcher also emphasised the need for #robust methods and the necessity to #harmonize globally the quality of qualification of techniques and validation of criteria. He also mentioned the current obstacles to the acceptance of these new methods and social barriers, notably in regulatory toxicology. 🌟 The interview reflects both the positive and constructive vision of the researcher, and his enthusiasm regarding the evolution of biomedical research and the potential of OoC technology. Read the full interview EN➡️https://lnkd.in/eedsDxFF FR➡️https://lnkd.in/ey6A55p3 Subscribe to our quarterly review (in french) https://lnkd.in/e28sU-9j

Luminex® assays have been a powerful tool in multiplexed biomarker detection, offering researchers the ability to simultaneously analyze multiple analytes with high precision. The improved sensitivity of the #INTELLIFLEX instrument allows for an even more #precise and #reliable detection of low-abundance biomarkers, providing researchers with more accurate and comprehensive data.  This advanced #sensitivity is crucial in complex biological samples where detecting subtle changes in #biomarker levels can be pivotal. Such improvements not only enrich the #quality of the data but also broaden the scope of possible research applications. By leveraging the INTELLIFLEX’s enhanced sensitivity, researchers can uncover deeper insights into biological processes, making it a valuable tool in both basic research and clinical diagnostics. This paper explores how the INTELLIFLEX’s High Sensitivity mode paired with Bio-Techne´s R&D Systems™ Luminex assays, can be utilized to its fullest potential, enhancing experimental outcomes and advancing scientific discovery. Download your copy here: https://lnkd.in/ezi8Wj6c

🧪 Trailblazing biomimicry: Bailey Richardson and a new era of medical applications 🧪 At the intersection of innovation and medical science, PhD student Bailey Richardson in the QUT Centre for Materials Science is pioneering a future where biomimetic chemistry transforms healthcare. Bailey's work, focusing on peptide self-assembly controlled photoreactivity, heralds a new era of medical applications, from targeted drug delivery to precision diagnostics. Read the latest #COSMOS article to discover what fuels Bailey's passion for biomimetic chemistry: https://bit.ly/3ISIIRc