Laurent Garosi’s Post

MRI OF METABOLIC AND NEURODEGENERATIVE ENCEPHALOPATHIES Fantastic multicentre descriptive study published in Frontiers in Veterinary Science by Maria Miguel-Garces under the supervision of our Vet Oracle Teleradiology head of neuroimaging Ines Carrera. This paper provides an excellent resource to help in the MR diagnosis of metabolic and neurodegenerative encephalopathies. Have a go at trying to identify these conditions on the images below! https://lnkd.in/eJuyNQ3g Enjoy the reading. Highly recommend!

GRANULOPRIVAL CEREBELLAR CORTICAL DEGENERATION Nice case report published as early view in JVIM by Thomas Mignan from Dovecote Veterinary Hospital, UK, and colleagues. The MRI of one of the cases presented was initially submitted to us at Vet Oracle Teleradiology and reported by Prof Simon Platt. Cerebellar cortical degeneration (CCD) described a group of diseases characterised by postnatal degeneration predominantly affecting the cerebellar cortex. CCD is classified according to the primary cell target. Both dogs in this case report were immature dogs with progressive cerebellar signs. MRI revealed in both dogs reduced volume of the cerebellar and widening of the cerebellar fissure. Histopathological examination identified marked diffuse thinning of the granular cell layer with almost complete loss of the granular cell neurons, providing a definitive diagnosis of granuloprival CCD. For further reading: https://lnkd.in/eq_bDuK2

Myxomatous mitral valve disease (MMVD) is the most common heart disease in dogs, and remains a debilitating condition despite recent advances in its treatment and management. We recently funded a master’s degree by research at The Royal (Dick) School of Veterinary Studies to determine whether arteries from dogs with MMVD show the same problems with constricting and dilating seen in humans with heart disease. Student Marco Mazzarella describes successfully validating the ‘gold standard’ technique of isometric myography to measure arterial endothelial dysfunction and explains how project findings could improve understanding of disease pathophysiology and help identify new therapeutic targets for MMVD. Read more: https://ow.ly/eRIf50U5gbU

😩 Traditional diagnostics for infectious diseases in veterinary medicine can often leave us feeling uncertain and overwhelmed. Do you ever doubt if you've selected the right pathogens or explored all possible infectious diseases that could be affecting your animals? 🤲🏼 We understand that feeling of insecurity, which is why we created PathoSense. This groundbreaking assay utilizes nanopore sequencing to provide a comprehensive diagnosis of all viruses and bacteria without the need for prior selection. 🚀 Join us for our upcoming webinar to discover how PathoSense can bring clarity and peace of mind to your diagnostic process! https://hubs.la/Q02qdr270

The July (61(4)) issue of Veterinary Pathology is currently available online. The issue has an incredible breadth or articles on swine models in biomedical research, SARS-CoV-2 in nondomestic felids, Mannhemmia-associated abomasitis in lambs, and myeloid hyperactivation in humanized mice (just to name a few). https://lnkd.in/g_B7GpAR

With March well underway, there has been several interesting papers published online in Veterinary Pathology on a variety of topics including (a) macrophage polarization in bovine and porcine tuberculosis, (b) experimental pollen beetle-associated gastroenteritis in cattle, (c) Neisseria-associated embolic pneumonia in cats, and (d) Mannheimia haemolytica-associated abomasitis in lambs.

How long do steroids interfere cortisol levels to diagnose hypoadrenocorticism in our patients? Did you know that even relatively short courses of prednisolone or other intermediate-acting steroids (> 7 days) can impact cortisol levels in dogs after discontinuation? A recent study found that while some dogs recover HPA (hypothalamic-pituitary-adrenal) axis function within a few days of stopping glucocorticoids, others take much longer—sometimes over 8 weeks! This variability can complicate interpretation of cortisol levels, especially when assessing for hypoadrenocorticism (Addison’s disease). In addition, recovery time was not linked to drug choice, dose, frequency, or even patient size. If you want to know more, join us today at 1pm UK time to discuss this and more in the Small Animal Medicine Hub. Sign up via bit.ly/4bc0X0y #SAMEhub #CanineHealth

❓ How to tackle the diagnostic challenges of thrombocytopenia and anemia of animal patients? Meet Dr. Olgun Aslan, owner of Kemer Veterinary Clinic in Türkiye, boasting a 22-year legacy, and also the founder of VetTalks and previous Vice President of TuVECCA. 👏 Thanks to the comprehensive parameters of BC-60R Vet, Dr. Olgun Aslan can effortlessly overcome the diagnostic challenge of thrombocytopenia and swiftly identify the type, severity, and underlying mechanism of anemia! 🐈 Detecting blood abnormalities in a single test！ #BC60RVet #mindrayanimalmedical #Hematology #bloodtest

Very proud on the recent publication of our study on 'Effect of rhTSH on radioactive iodine uptake by thyroid carcinoma in dogs' in the Journal of Veterinary Internal Medicine. Thank you Prof. Dr. Sylvie Daminet and Dr. Kathelijne Peremans to have supervised me in this last and main chapter of my PhD. Faculteit Diergeneeskunde UGent #PhD #VeterinaryResearch #Oncology

👏Un grand bravo au Dr Moranne Frejlich venue représenter notre service d'ophtalmologie lors de l’ ECVO (European College of Veterinary Ophthalmologists) annual Meeting, à Amsterdam, et présenter différents travaux menés en équipe avec le Dr Guillaume Payen :   - A prospective study of the association of anaemia and thrombocytopenia with ocular lesions in cats M. Frejlich ; A.E. Grillot ; G. Payen   - The prevalence and characteristics of feline ulcerative keratitis in a referral population and the comparison between brachycephalic and non-brachycephalic cats – a retrospective study M. Frejlich ; G. Payen   - Sino-orbital aspergillosis in a cat caused by Aspergillus Versicolor with intracranial involvement M. Frejlich ; E. Gomes ; G. Payen   #ECVOmeeting #ophtalomogievet