Novalix’s Post

Publication of the Day 📚 "Efficient and Sustainable Electrosynthesis of N-Sulfonyl Iminophosphoranes by the Dehydrogenative P–N Coupling Reaction" from JACS AU. Why are Iminophosphoranes Important ? 🔍 They play an important role in organic chemistry due to their versatility as intermediates in the synthesis of various nitrogen-containing compounds. They are notably used as nitrene donor. The Reaction and Mechanism ⚙️ - Electrooxidation : The phosphine is oxidized at the anode. - Coupling : The oxidized phosphine reacts with the sulfonyl azide to form the iminophosphorane. - Dehydrogenation : Hydrogen gas is released as a byproduct, making the process clean and sustainable. Advantages of This Method ⚗ - Sustainability : Uses electricity instead of traditional chemical oxidants, reducing waste. - Efficiency : High yields and selectivity for the desired products. - Scalability : Suitable for large-scale synthesis, which is vital for industrial applications. At NUVISAN The Science CRO, our team of process chemists is dedicated to provide route scouting, process development, GMP manufacturing alongside impurities and solid state studies. Contact me to know more ! 👩🔬 👨🔬 #Chemistr #OrganicChemistry #Electrosynthesis #SustainableChemistry #Innovation #OpenAccess #JACS #DrugDevelopment #Nuvisan

I invite everyone who is interested, to join me for giving some insights into our work on industrial biocatalysis at Enzymicals.

Who's the mastermind behind the SBP kits? Ofir Menashe, the founder of Bio-Capsules, stands at the forefront. A graduate of The Technion - Israel Institute of Technology with a Ph.D. in Microbiology & Biotechnology, Ofir's journey began with a passion for harnessing microorganisms to solve environmental challenges. Early on, he recognized the need for new methods to encapsulate commercially viable bacteria for effective field application. During the development of SBP technology, Ofir encountered significant development challenges. Through iterative trials and persistent effort, Bio-Capsules successfully developed SBP technology, which not only innovatively encapsulates microorganisms but also facilitates complex experiments previously considered impractical with live bacteria. Overcoming these development challenges, Ofir and his team have conducted rigorous trials, lasting months, addressing critical needs in wastewater treatments and complex fermentation systems. The technology will be integrated into a variety of research disciplines including: environmental engineering, chemical engineering, biotechnology, life sciences, medicine, and more. Join Ofir Menashe and the Bio-Capsules team on their journey of innovation and practical solutions in biotechnology. #Biocontrol #SBPKits #Agriculture #Research #Innovation #Sustainability #chemicalengineering #biotechnology #medicine #watertreatment

Assalamualaikum and greetings for a wonderful day. With high spirits from the start of the new semester in UiTM, I concluded my first task in the Biocatalyst class taught by Dr. Amizon Azizan. Thank you for allowing me to learn more in-depth about this topic. This poster will help you to gain a better understanding of the difference between biocatalysts and chemical catalysts. References: 1. Biocatalysis by Elizabeth L. Bell and William Finnigan (Nature, Jun 2021) 2. Biocatalysis: Enzymatic Synthesis for Industrial Applications by Shuke Wu and Jeffrey C Moore (ResearchGate, Jun 2020) 3. Speeding up reactions: biological vs chemical catalyst by S.E. Gould (SCIAM, January 2014) #biocatalyst #biocatalysis #bioprocess #chemicalengineering #decarbonization #industry #engineering #reactor #bioreactor #sustainability

𝐃𝐨𝐧'𝐭 𝐟𝐨𝐫𝐠𝐞𝐭 𝐭𝐨 𝐫𝐞𝐠𝐢𝐬𝐭𝐞𝐫 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐚𝐝𝐯𝐚𝐧𝐜𝐞𝐝 𝐜𝐨𝐮𝐫𝐬𝐞 𝐨𝐧 𝐁𝐢𝐨𝐜𝐚𝐭𝐚𝐥𝐲𝐬𝐢𝐬 𝐚𝐧𝐝 𝐏𝐫𝐨𝐭𝐞𝐢𝐧 𝐄𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐢𝐧𝐠 𝐭𝐡𝐢𝐬 𝐲𝐞𝐚𝐫! 💡 Advanced Course on Biocatalysis and Protein Engineering 📓 7-11 April 2025 📌 Delft the Netherlands The Advanced Course Biocatalysis and Protein Engineering aims to familiarize participants with the integrated, interdisciplinary approach required to utilize the catalytic potential of enzymes and whole cells for the production of useful compounds. Organic chemists, enzymologists, microbiologists and (bio)chemical engineers from the faculty staff of Delft University of Technology and other universities, together with invited international experts from industry, will offer a selection of theory and practice. In this way, the course will provide an intensive and in-depth treatment of the state of the art and the necessary link between fundamental knowledge and practical applications in industrial scale processes. Course board: Ulf Hanefeld, Frank Hollmann, Caroline E. Paul, Adrie Straathof and Peter-Leon Hagedoorn More information can be found on our website; https://lnkd.in/e3mftaYM See our program below for more information regarding this post #biocatalyse #protein #engineering #biocatalysis #catalytic

✨ All good things come to an end — yet leave a lasting impact! 🎉 The MACBETH Project concluded with a final consortium meeting in Dortmund, celebrating five years of groundbreaking achievements and collaboration. 🌍 A newly released project video highlights its remarkable journey and sustainable contributions, particularly the development of the catalytic membrane reactor — a technology transforming the chemical processing industry. Our CEO, Dr. David Liese, proudly shared our joint success in biocatalytic oil cleavage using membrane separation technology. This innovation has the potential to revolutionize downstream processing of waste fish oil with low omega-3 fatty acid content. 🔬 The end of the project is just the beginning — protein engineering holds the key to unlocking the full potential of this approach. 🎥 Watch the full video here: https://lnkd.in/dJWG8Tt6 #biocatalysis #greenchemistry #enzymes #BiotechInnovation #BOCcase #EU #H2020

"Exploring the Versatility of the Petasis Reaction in Advanced Organic Chemistry" In the realm of organic synthesis, the Petasis reaction stands out for its efficiency and adaptability. This multicomponent reaction allows the formation of α-amino acids and their derivatives through the reaction of amines, aldehydes (or ketones), and boronic acids.The beauty of the Petasis reaction lies in its wide range of applications, from drug discovery to complex natural product synthesis. Its ability to work under mild conditions and tolerate a variety of functional groups makes it a valuable tool in the chemist's arsenal.As we continue to push the boundaries of synthetic organic chemistry, reactions like Petasis are key to innovating new pathways and solutions. Whether you're designing a new synthetic route or exploring alternative methods for complex molecule construction, the Petasis reaction offers a robust and flexible approach.#OrganicChemistry #PetasisReaction #SyntheticChemistry #DrugDiscovery #AdvancedSynthesis

Electrodialysis and Bipolar Membrane Electrodialysis: Empowering the Biopharmaceutical Industry to Achieve ESG Excellence #BIOCHINA2024 #ESG #Exhibition #Electrodialysis #SyntheticBiology #BiotechInnovation #FermentationTechnology #Desalination #SustainableTech #WastewaterTreatment #OrganicAcids #FoodGradeChemicals

See below a very interesting Advanced Course on Biocatalysis and Protein Engineering.

🎓 University of Tartu is offering a fully-funded #PhD position within the prestigious #MSCA program, focused on Catalytic Enhancement of Anaerobic Ammonium Oxidation for Nitrogen and Pharmaceutical Removal in Wastewater. Under the supervision of Prof. Ivar Zekker, this research aims to harness the power of nanomaterials to boost Anammox processes. The project will explore the use of biomass-derived nano-structured carbonaceous substances (n-CCSs) to enhance the degradation of pharmaceutically active compounds (PhACs), while also improving nitrogen removal efficiency. 🔬 You’ll investigate both suspended and immobilized n-CCSs, studying their impact on microbial community dynamics, PhAC degradation, and bioelectrochemical systems (BES) to optimize removal processes. This is a unique opportunity to advance your career in environmental biotechnology, contributing to real-world solutions for sustainable wastewater treatment. 🚀 📍 Learn more and apply now at: https://lnkd.in/d6SH6MKp #PhDopportunities 🎓 #MSCA #Nanotechnology ⚛️ #WaterTreatment 💧 #Sustainability 🌿 #EnvironmentalScience 🌍 #Research 📚 #WastewaterInnovation 🚀 #Anammox