PluriCells’ Post

Pluripotent stem cells or myoblasts – Do PSCs have a higher risk profile? Latest PluriCells blog provides insights into pluripotent stem cells and myoblasts, providing research data to answer critical questions on the topic. Read the blog ➡️ https://lnkd.in/eGtjWV3t https://lnkd.in/eGtjWV3t

Goodbye, Diabetes? Cells from fatty tissues can now be turned into cellules productrices d'insuline . Scientists have developed a groundbreaking method to transform stem cells from fatty tissues into insulin-producing cells, offering a potential new treatment for diabetes. These cells mimic the function of pancreatic beta cells, which are responsible for producing insulin in the body. This discovery could help restore insulin production in individuals with diabetes, potentially reducing their dependence on external insulin injections and improving their overall quality of life. This technique leverages the body's own fat cells, making it a less invasive and more accessible approach to developing new therapies. The ability to reprogram these stem cells into functional insulin producers is a major step forward in regenerative medicine and could lead to personalized treatments for diabetes in the future Read More: http://bit.ly/1XtX9vx Research Paper: http://bit.ly/1Nnbqo4

Stem Cell Manufacturing Market Size to reach $21.8 billion by 2028 𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐭𝐡𝐞 𝐏𝐃𝐅 𝐁𝐫𝐨𝐜𝐡𝐮𝐫𝐞 𝐚𝐭 https://lnkd.in/dAm--4fH The global stem cell manufacturing market in terms of revenue was estimated to be worth $12.7 billion in 2023 and is poised to reach $21.8 billion by 2028, growing at a CAGR of 11.3% from 2023 to 2028. Key Players: MIDSCI UCT MedTech ICCBBA 3DBioFibR Inc. Hycult Biotech Department of Biomedical Engineering at TU/e Leinco Technologies France-BioImaging Laboratory for Molecular Cell Biology, UCL Mechanobiology Institute IWA Consulting Aglaris Ltd Group myriamed GmbH NEST Scientific USA STELLα, a Ronawk Company BioSim Innovations Analytical Biological Services Inc. (ABS Inc.) Neova Technologies Inc. Cellivia Lifecycle Biotechnologies, LP CR2TI UMR 1064 Nantes Harper Cancer Research Institute GIOSTAR Chicago SunP Biotech CellASIC VitaCyte Veterinary Transplant Services, Inc. Center of Excellence for Research in Regenerative Medicine and Applications The MTM Laboratory Predictive Technology Group Inc

Tubular bowl centrifuges offer manufacturing advantages during media exchanges in the cultivation of induced pluripotent stem cells (iPSCs), addressing the critical aspects of cell viability, health, and controlled differentiation. Read the full article here: https://lnkd.in/gpxuT2Uv #CARRBiosystems #Centrifugation #SingleUseCentrifuge #celltherapy #bioprocessing #allogeneic #genetherapy #cellandgenetherapy #lifesciences #mediaexchanges

🔬 Unlocking the Potential of Human Pluripotent Stem Cells Within the intricate landscape of regenerative medicine, human pluripotent stem cells (hPSCs) stand as a beacon of hope, offering unprecedented potential for transformative therapies. However, the journey towards harnessing their power is accompanied by the critical imperative of ensuring their genetic stability. Learn more to see how the industry is navigating the latest advancements and challenges in maintaining genetic integrity throughout the lifecycle of hPSCs. Read more here: https://lnkd.in/gA3QS3Y2 #OCBio, #OrangeCountyBio, #CGT, #CellandGeneTherapy, #CellTherapy, #CARTTherapy, #CART, #GeneTherapy, #Consulting, #Marketing, #Stemcells

🚨 𝐀𝐫𝐞 𝐲𝐨𝐮 𝐬𝐭𝐫𝐮𝐠𝐠𝐥𝐢𝐧𝐠 𝐰𝐢𝐭𝐡 𝐲𝐨𝐮𝐫 𝐜𝐞𝐥𝐥 𝐩𝐫𝐞𝐬𝐞𝐫𝐯𝐚𝐭𝐢𝐨𝐧 ? We've handpicked the top 4 tools to ensure you never have to worry about cell viability post-thawing again. Discover how to optimize your cell preservation process and achieve consistent results! ❶ #𝐂𝐫𝐲𝐨𝐩𝐚𝐧 𝐈𝐈 - 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐩𝐚𝐫𝐭𝐧𝐞𝐫 PAN-Biotech GmbH This chemically defined and protein-free freezing medium is specifically designed to ensure optimal cell preservation. ✅ Versatility: Perfect for freezing both adherent and suspension cells. ✅ Superior composition: A blend of salts, sugar, 10% DMSO, and antifreeze substances, free from any animal or human components. ✅Exceptional viability: The serum-free formulation is tailored for preserving serum-free cultured cells, guaranteeing high cell viability post-thawing. 💚 Ideal for : - Stem Cell Research and Therapy - Tissue Engineering - Cellular Therapies - #Biobanking - Gene Therapy - Research and Development - Vaccine Production ❷ 𝐂𝐎𝐎𝐋𝐁𝐎𝐗 & 𝐂𝐎𝐎𝐋𝐑𝐀𝐂𝐊 - 𝐟𝐫𝐨𝐦 Corning LifeScience Build your cooling solution – it’s as easy as 1-2-3. 1 – First select your consumable type. 2 – Select a Corning CoolRack® module based on your consumable and sample quantity. 3 – Match with the appropriate ice-free Corning CoolBox or ice bucket/pan solution. ❸ 𝐂𝐑𝐘𝐎𝐆𝐄𝐍𝐈𝐂 𝐕𝐈𝐀𝐋𝐒 - 𝐟𝐫𝐨𝐦 Corning Choose Sustainability with Corning #Cryovials From production to disposal, Corning Cryovials are designed with the environment in mind. Every step of the process is optimized to reduce environmental impact, making it easier for you to make eco-friendly choices in your lab. ❹ 𝐂𝐎𝐎𝐋𝐂𝐄𝐋𝐋 𝐂𝐎𝐍𝐓𝐀𝐈𝐍𝐄𝐑𝐒 - 𝐟𝐫𝐨𝐦 #𝐂𝐨𝐫𝐧𝐢𝐧𝐠 Better than IPA ✅No alcohol (No fluids - No pre-cooling - Saves 12L/unit of IPA per year) ✅No variability (All vials have uniform freeze rate - Radially symmetric design ensures vial consistency) ✅No on-going cost (No alcohol purchase or disposal) ✅No stuck lids (Ergonomic lid comes off easily when frozen - Not cold to the touch when removing from the -80˚C freezer) ✅Quick re-use time (Ready to use again after five minutes) 👉Don’t let poor cell viability hold back your research. Learn more about our solutions and elevate your cell preservation today! #CellPreservation #BiotechSolutions #LabEfficiency #chemiebrunschwigag #panbiotech

𝙃𝙤𝙬 𝙩𝙤 𝙢𝙖𝙞𝙣𝙩𝙖𝙞𝙣 𝙨𝙩𝙚𝙢 𝙘𝙚𝙡𝙡 𝙘𝙪𝙡𝙩𝙪𝙧𝙚𝙨 𝙢𝙤𝙧𝙚 𝙚𝙛𝙛𝙞𝙘𝙞𝙚𝙣𝙩𝙡𝙮 𝙖𝙣𝙙 𝙝𝙤𝙢𝙤𝙜𝙚𝙣𝙚𝙤𝙪𝙨𝙡𝙮? #Stemcell maintenance requires the proper activation of FGF signalling, as the growth factor FGF-2 is involved in a variety of biological processes, including embryonic development, neural differentiation, and the proliferation of cells of mesodermal origin 🧬 👉 Therefore, the addition of exogenous FGF-2 is required to sustain stem cell self-renewal, and their capacity to differentiate into a large number of somatic cell types. Still, the application of commonly commercialized FGF-2 is limited due to its rapid loss during cultivation, as extensive research studies have shown FGF-2 to be unstable at physiological conditions, with a half-life of approximately 8 h in mammalian cell culture 🧫 As such, the need for a FGF-2 product with excellent stability is essential -specially as the field of stem cell research and manufacturing continues moving towards serum-free / chemically defined cell culture media conditions 🧪 Core Biogenesis is pleased to provide one of the most advanced options in the market to integrate a highly stable FGF-2 molecule to achieve #consistency during #StemCellCultures. Our star product 𝗙𝗚𝗙-𝟮 𝗧𝗢𝗣® (𝗧𝗵𝗲𝗿𝗺𝗼𝘀𝘁𝗮𝗯𝗶𝗹𝗶𝘁𝘆 𝗢𝗽𝘁𝗶𝗺𝗶𝘇𝗲𝗱), is available to satisfy all the demands and needs from the research to the clinical manufacturing stages, now being also developed in #GMPgrade in collaboration with our partner, Nucleus Biologics. ⏩ Scroll to have a glimpse of the amazing attributes and performance of FGF-2 TOP® (𝘛𝘩𝘦𝘳𝘮𝘰𝘴𝘵𝘢𝘣𝘪𝘭𝘪𝘵𝘺 𝘖𝘱𝘵𝘪𝘮𝘪𝘻𝘦𝘥) 𝚈𝚘𝚞 𝚌𝚊𝚗 𝚕𝚎𝚝 𝚞𝚜 𝚔𝚗𝚘𝚠 𝚢𝚘𝚞𝚛 𝚒𝚗𝚝𝚎𝚛𝚎𝚜𝚝 𝚏𝚘𝚛 𝚎𝚟𝚊𝚕𝚞𝚊𝚝𝚒𝚘𝚗 𝚊𝚝 𝚢𝚘𝚞𝚛 𝚍𝚎𝚜𝚒𝚛𝚎𝚍 𝚐𝚛𝚊𝚍𝚎 𝚋𝚢 𝚌𝚘𝚗𝚝𝚊𝚌𝚝 𝚞𝚜 𝚑𝚎𝚛𝚎: https://lnkd.in/eXTG3S8h #StemCells #Research #CellTherapy #GrowthFactors #SustainableSciene

Who are the stem cell players that matter? ✨ Over the years the stem cell therapy market has gained traction and is valued at $12.4 billion in 2024 and is expected to reach $18.5 billion by 2029. With the increasing incidence of chronic and degenerative diseases, demand for stem cell treatment with reparative and regenerative properties is high. 🧬 The development of induced pluripotent stem cells and mesenchymal stem cells has allowed the creation of off-the-shelf cell therapies, more accessible and scalable. 📈 In this article, we delve into the companies to know about in this evolving field! ⬇️ https://lnkd.in/d2wD83QS #stemcelltherapy #regenerativemedicine #biotech #healthcareinnovation #chronicdiseases #degenerativediseases #celltherapy #biotechcompanies #stemcellresearch #medicalinnovation Aspen Neuroscience, Inc. | BlueRock Therapeutics | Cellino | Fate Therapeutics Inc. | Garuda Therapeutics | Mesoblast Limited | Orca Bio | Sana Biotechnology, Inc.

🧬 Exciting news from the world of stem cell research! A recent study demonstrates how induced pluripotent stem cells (iPSCs) culture can be efficiently scaled up using microcarriers, achieving a higher expansion rate compared to traditional aggregate methods. 🌟 This innovative approach opens up new possibilities for advancing research and application in regenerative medicine, drug discovery, and beyond. 🚀 Interested in elevating your iPSCs culture to the next level? Get in touch with Smart MCs for cell-type specific and customised microcarrier solutions designed to optimize your research. 🌐 Let's innovate together for a healthier future! 💡 #StemCellResearch #iPSCs #RegenerativeMedicine #Biotechnology #Innovation #SmartMCs #ScienceandTechnology Read More: https://lnkd.in/gChqbDfE

🔬𝔹𝕣𝕖𝕒𝕜𝕚𝕟𝕘 𝔹𝕠𝕦𝕟𝕕𝕒𝕣𝕚𝕖𝕤: 𝔻𝕚𝕤𝕔𝕠𝕧𝕖𝕣 𝕥𝕙𝕖 𝔾𝕒𝕞𝕖-ℂ𝕙𝕒𝕟𝕘𝕚𝕟𝕘 𝕀𝕟𝕟𝕠𝕧𝕒𝕥𝕚𝕠𝕟𝕤 𝕚𝕟 𝕊𝕥𝕖𝕞 ℂ𝕖𝕝𝕝 𝕋𝕙𝕖𝕣𝕒𝕡𝕪 𝕋𝕖𝕔𝕙𝕟𝕚𝕢𝕦𝕖𝕤! 1.𝙸𝚗𝚍𝚞𝚌𝚎𝚍 𝙿𝚕𝚞𝚛𝚒𝚙𝚘𝚝𝚎𝚗𝚝 𝚂𝚝𝚎𝚖 𝙲𝚎𝚕𝚕𝚜 (𝚕𝙿𝚂𝙲𝚜): IPSCs are adult cells transformed into versatile stem cells, tailor-made for each patient, reducing immune rejection risks. 2. 𝙲𝚁𝙸𝚂𝙿𝚁/𝙲𝚊𝚜9 𝙶𝚎𝚗𝚎 𝙴𝚍𝚒𝚝𝚒𝚗𝚐 : Gene editing ensures precise correction of genetic flaws present in stem cells before they are used for therapy elevating therapy safety. 3. 𝙴𝚡𝚘𝚜𝚘𝚖𝚎 𝚃𝚑𝚎𝚛𝚊𝚙𝚢 : Exosomes are small vesicles secreted by stem cells that contain proteins, nucleic acids & other molecules. These exosomes play a crucial role in mediating the therapeutic effects of stem cell therapy. 4. 𝚖𝚒𝚌𝚛𝚘𝚏𝚕𝚞𝚒𝚍𝚒𝚌 𝚍𝚎𝚟𝚒𝚌𝚎𝚜 𝚊𝚗𝚍 𝙱𝚒𝚘𝚙𝚛𝚒𝚗𝚝𝚒𝚗𝚐 : Advances in these technologies enables precise assembly of stem cells into complex tissue structures. 5.𝙾𝚛𝚐𝚊𝚗𝚘𝚒𝚍 𝙲𝚞𝚕𝚝𝚞𝚛𝚎 𝚂𝚢𝚜𝚝𝚎𝚖𝚜 : Organoid are miniature, 3-D organ-like structures derived from stem cells which replicates human organs, offers a platform to study diseases & drug responses effectively. 6. 𝚃𝚊𝚛𝚐𝚎𝚝 𝚍𝚎𝚕𝚒𝚟𝚎𝚛𝚢 𝚜𝚢𝚜𝚝𝚎𝚖𝚜 : Researchers are developing innovative delivery systems to enhance the targeting & retention of stem cells at injury site.This includes engineered biomaterials, nanoparticles maximizing healing potential. Join the journey toward a future of personalized, effective healthcare! #StemCellTherapy #RegenerativeMedicine #HealthcareInnovation #MedicalBreakthrough #CuttingEdgeScience #HealthTechAdvances #ScienceRevolution #BioTechBreakthrough #FutureOfHealthcare