Polyphenols World Congress’ Post

✨ Our paper is published in Green Chemistry (Royal Society of Chemistry)! We present a sustainable biocatalytic process for the one-pot synthesis of Ribose-1-phosphate (Rip1P), a key substrate for the synthesis of new nucleoside-based drugs (e.g., antibiotics). However, its use in preparative synthesis has been hampered by low yields and low selectivity during conventional methods (also reflected in the high price). By coupling a guanine deaminase to the nucleoside phosphorylase-catalysed guanosine (Guo) cleavage, the reaction shifted towards almost complete Guo cleavage. Our cascade approach reduced the need for toxic reagents and purification steps inherent to previous methods, reducing the environmental burden of the route. Big thanks to all the authors: Sarah Westarp, Jonas Barsig, Christina Betz, Amin Dagane, Felix Kaspar, Lena Neumair, Sebastian Kemper, Peter Neubauer, and Anke Kurreck 📄 Please have a read (it is open access): https://lnkd.in/e6XC7wXJ Chair of Bioprocess Engineering-TU Berlin Einstein Foundation Berlin UniSysCat - Cluster of Excellence #biocatalysis #GreenChemistry #nucleosides

🎉 We are thrilled to announce the publication of our latest research article, titled "Maximizing Photocatalytic Efficiency with Minimal Amount of Gold: Solar-driven TiO2 Photocatalysis Supported by MICROSCAFS® for Facile Catalyst Recovery." 👩🔬 In this study, we present MICROSCAFS®, SiO2-TiO2 microsphere with interconnected meso and macroporosity, as robust and efficient catalyst support. The research focuses on the application of MICROSCAFS® for solar-driven photocatalysis, offering a promising solution for wastewater purification, along with easy catalyst recovery and reuse. 🥇 Moreover, adding a low amount of gold nanoparticles improved the overall photocatalytic efficiency by 20%. Yes, gold nanoparticles are simply Au-some 😎. 🌟 A huge congratulations to each of our co-authors, and a special shoutout to the main author, Sofia M., on her debut as the main author! 📚 Article Details: 🔗 DOI: 10.1016/j.jece.2024.112043

Check out our last contribution in Agewandte Chemie: Controlling Monoterpene Isomerization by Guiding Challenging Carbocation Rearrangement Reactions in Engineered Squalene‑Hopene Cyclases This is the outcome of years of research by Prof. Hauer's group. I'm glad that we could contribute with computational insights on the selectivity of SHC towards the isomerization of monterpenes. #biocatalysis #moleculardynamics #mutagenesis #terpenes #computationalchemistry #enzymes

🚨 New paper released! Great collaboration between Unité Mixte de Recherche FARE, INRAE BIA, BBF Marseille and BIBS platform INRAE. Oxidative enzymes play an important role in degrading lignocellulosic biomass, but the modifications they carry out are often difficult to localize and quantify in situ on a cellular scale. We applied a MALDI-MS imaging method to detect oxidized oligosaccharides released by an oxidative cellulose enzyme (#LPMO) on corn stalk tissues, at the cellular scale. The results obtained enabled us to image the action of LPMO and measure the spatial variation and relative abundance of oxidized and non-oxidized oligosaccharides. LPMO thus has a targeted action linked to the composition and organization of plant cell walls. This approach opens up possibilities for better studying and understanding the synergistic effects of various hydrolytic and oxidative enzymes on lignocellulosic wall degradation, with a view to improving enzyme cocktails for biotechnological applications. This work was made possible by the funding of Région Grand Est and Communauté urbaine du Grand Reims of Amandine Leroy #PhD thesis directed by Fabienne Guillon and Gabriel Paës, in collaboration with Jean-Guy Berrin, Sacha Grisel, Mireille HAON, Hélène Rogniaux, Mathieu Fanuel, and Camille Alvarado.

📰 Publication Alert! ⚗ Mix #biobased #lactic acid and #thiolactic acid with a suitable Brønsted acid catalyst, and the result is a novel #monomer for the #bioplastics industry: monothiolactide (OS), composed of half a lactide (OO) unit and half a thiolactide (SS) unit. This new monomer and its #polymer combine the benefits of esters and thiolesters, highlighting superior #chemical #recycling ♻ and hydrolytic degradation properties compared to #polylactide and #polythiolactide. 🤝This work is a joint effort between the Dusselier Lab at KU Leuven and the University of Lorraine. Warm congratulations to our colleagues An Sofie Narmon, Liliana Jenisch, Ibrahim Khalil, Michiel Dusselier, and collaborators Jérôme Rey and Michael Badawi. Credits go to Gleb Ivanushkin for the conception of the lovely graphical abstract. Thanks! With, among others, a shout out to B4Plastics, VLAIO - Flanders Innovation & Entrepreneurship, and Research Foundation Flanders - FWO for their funding of this work! Interested ❓ Please take a look: https://lnkd.in/ec-3R7x8 🌍 Follow us for more about #zeolites, #CO2 valorization, #bioplastics, #heterogeneous #catalysis, and #spectroscopy!

Hi LatinXChem presenting my work "TiO2-catalyzed Direct of Cyclic Dicarbonyls with Diazonium Salts" at #LatinXChem24 #LatinXChemOrg #Org016 #Heterogeneouscatalysis #Directdiazenylation To learn more about my research group: Laboratório de Síntese Orgânica Aplicada (LabSOA)

Join the waitlist for the 450Hi Light Module today and learn how it can 3x the original light intensity of your Photoreactor m2: https://ow.ly/Q55I50RhklM #Biochemistry #PharamceuticalResearch #OrganicChemistry

Discover the critical role of #biologicalbuffers in scientific research 🧬   At DC Fine Chemicals we provide a comprehensive range of biological buffers to ensure precise and reproducible results in your experiments. Explore our extensive range of biological buffers here: https://bit.ly/4eAzJmk   If you require further information, please don’t hesitate to contact us at info@dcfinechemicals.com.   #biologicalbuffers #finechemicals #biochemistry #cellculture #adifferentkindofchemistry

"One-Pot Three-Component Synthesis of Biologically Promising Indenoquinoxaline Fused Spiroheterocycles Starting from 11H-indeno[1,2-b]quinoxalin-11-ones" by Bubun Banerjee et al Source:  https://lnkd.in/g9GB5mE6 https://lnkd.in/gsVPQn-q #spiroheterocycles #One_pot_three_component_synthesis #indenoquinoxaline_fused_spiroheterocycles

My second article in 2024 is devoted to microspheres covered with carbon dots. This is still a new material that is supposed to be low-toxic. At the surface of microspheres of only 5-7 um diameter, carbon dots show emission corresponding to whispering gallery modes (with decent Q-factors for such systems). Such spheres may be applied for in vivo biosensing; atm they were tested with bovine serum albumin. The work originates from our discussions back in 2021. Even though it is 2024, my friends from ITMO and the Institute of Macromolecular Compounds noted my earlier contribution, thanks.