Rare Disease Diversity Coalition’s Post

Value of [ 18F]AlF‑NOTA‑FAPI‑04 PET/CT for differential diagnosis of malignant and various inflammatory lung lesions: comparison with [ 18F]FDG PET/CT. https://lnkd.in/eAkrUm8w

Did you know that REMS technology can be used in some clinical situations where traditional DXA scans might fall short? In a paper on fragility score, Echolight’s REMS-based Bone Mineral Density (BMD) T-score was able to measure a significantly lower BMD value in comparison to the DXA BMD T-score in fractured patients with secondary osteoporosis (caused by conditions like diabetes and anorexia). This suggests that REMS may be more sensitive in detecting reduced bone density in such patients. Echolight’s REMS technology offers precise measurements in patients with specific conditions like secondary osteoporosis, chronic kidney disease, and rheumatoid arthritis, making it a valuable tool in managing bone health. Discover more about Echolight - https://lnkd.in/eAU74XM5 #Echolight #EcholightintheWorld #REMS #REMStechnology #Osteoporosis #Osteodystrophy #Osteopenia #PatientCare #BoneHealth #SkeletalHealth #BoneDensity

There is a significant need for innovative pharmacological treatments in Systemic Sclerosis (SSc). A recent Spherix report shows nearly all rheumatologists rate the unmet need in SSc as “extremely high,” the highest among rheumatic diseases. With nearly half of patients not optimally managed, new treatments are crucial. ✨𝐈𝐬 𝐲𝐨𝐮𝐫 𝐩𝐢𝐩𝐞𝐥𝐢𝐧𝐞 𝐚𝐬𝐬𝐞𝐭 𝐩𝐨𝐬𝐢𝐭𝐢𝐨𝐧𝐞𝐝 𝐭𝐨 𝐦𝐞𝐞𝐭 𝐤𝐞𝐲 𝐞𝐧𝐝𝐩𝐨𝐢𝐧𝐭𝐬 𝐚𝐧𝐝 𝐬𝐭𝐚𝐧𝐝 𝐨𝐮𝐭 𝐢𝐧 𝐚 𝐜𝐨𝐦𝐩𝐞𝐭𝐢𝐭𝐢𝐯𝐞 𝐦𝐚𝐫𝐤𝐞𝐭? Reach out to learn more about our comprehensive report and how it can give your product the edge. #marketresearch #rheumatology #SSc

According to many authors, the incidence of osteomyelitis in the world is increasing, doubling its rate between the 1960s and the 2010s. Despite the growing number of publications in this area, this disease still represents a major challenge for orthopedists around the world. This study aimed to highlight the continued importance and utility of plain radiography as a rapid, cost-effective, and readily accessible examination in the diagnostic process. Our study shows that radiographic findings in chronic osteomyelitis were universally observed in all patients studied, demonstrating a high degree of concordance among specialists. #osteomyelitis, #boneinfection, #musculoskeletaldisorders https://lnkd.in/ez7ypaqK

Primary care physicians correctly diagnose #alzheimer’s disease about 61% of the time. Neurologists have an accuracy rate of about 73%. A new blood based test, relying on the pTau217 assay from ALZpath Inc., can accurately identify about 90% of cases. This is a great example of the importance of molecular #biomarkers, but it doesn’t stop there. Teal Omics is using molecules in the blood as a starting point to explore the complex networks that are impacted by diseases of #aging in order to develop more effective treatments than the ones that are available to patients today. Together, the field is moving toward a more sophisticated understanding of disease processes and the best ways to treat them. https://lnkd.in/g4h5tx4J

Effects of vildagliptin on wound healing and markers of inflammation in patients with type 2 diabetic foot ulcer: a prospective, randomized, double-blind, placebo-controlled, single-center study #ActAgainstAmputation @ALPSlimb https://lnkd.in/giaGZSHU

𝐓𝐞𝐦𝐑𝐄𝐍 𝐀𝐭𝐡𝐞𝐫𝐞𝐜𝐭𝐨𝐦𝐲 𝐒𝐲𝐬𝐭𝐞𝐦. 𝐑𝐎𝐓𝐀𝐓𝐈𝐎𝐍𝐀𝐋 𝐂𝐎𝐑𝐎𝐍𝐀𝐑𝐘 𝐀𝐓𝐇𝐄𝐑𝐄𝐂𝐓𝐎𝐌𝐘 𝐒𝐘𝐒𝐓𝐄𝐌 Peripheral arterial disease (PAD) is a clinical manifestation of systemic atherosclerosis and is associated with significant morbidity and mortality. The physiological force and shear stress from angioplasty and stenting have made PAD treatment challenging. TEMREN Atherectomy is a major therapy in the management of peripheral vascular disease.

The incidence of GA is projected to increase in the next 20 years due to an expanding elderly population and heightened awareness of the disease state. Join Daniel Epshtein, OD FAAO, and Mark Dunbar, OD, FAAO, on the latest episode of Ready, Set, Retina, as they discuss a case of geographic atrophy (GA) that received treatment with a complement inhibitor. Learn about the shifting GA treatment landscape, complement inhibition treatments, and more. https://hubs.ly/Q02LKGd00 #ReadySetRetina #optometrist

Living with Inflammatory Bowel Disease (IBD) can be challenging, but new advancements are helping to make diagnosis and monitoring less invasive.    Intestinal ultrasound—a non-invasive tool—is changing the game for patients with Crohn's disease and ulcerative colitis, offering real-time insights into the bowel's condition without the need for scopes or biopsies.    Read our latest article to learn how this innovation is already improving the quality of life for many by making care more accessible and less intrusive: https://lnkd.in/e8B_J8hH   #IBD #CrohnsDisease #UlcerativeColitis     Pfizer

Dr. Cecil Alport reported on a phenotype familial pattern of blood in the urine, kidney disease, and hearing loss termed "Hereditary Familial Congenital Haemorrhagic Nephritis" in 1927. This is referenced as the first publication that eventually has lead to establishment of "Alport syndrome". We have come some far! We have gone from 1st recognizing more severe X-linked and AR causes to dominant with reduced penetrance and variable expressivity presentations. See a recent review and the original 1927 publication links below. #genechat #Alportsyndrome #NKF https://lnkd.in/gYAmqHDV https://lnkd.in/gBgdefXy