Vesiculab’s Post

🌟 Excited to share the Title Story, Volume 9 Issue 12: Bioprocess Economic Modeling: Decision Support Tools for the Development of Stem Cell Therapy Products. 🥼 This paper is authored by William O. S. Salvador, Inês A. B. Ribeiro, Diogo E. S. Nogueira, Frederico C. Ferreira, Joaquim M. S. Cabral, and Carlos A. V. Rodrigues. 💡 The present work reviews important concepts concerning the development of bioprocesses for stem cell therapy products and highlights the valuable role which BEMs can play in this endeavor. Additionally, some theoretical concepts relevant to the building and structuring of BEMs are explored. Finally, a comprehensive review of the existent BEMs so far reported in the scientific literature for stem cell-related bioprocesses is provided to showcase their potential usefulness. Welcome to view this paper here👉 : https://lnkd.in/gysT5B8V. #bioprocess #modeling #cell_therapy #gene_therapy #stem_cell #manufacturing #bioprocess

Why we choose the MSCs //? Why not Embryonic Stem cell althouhg have many importance?/// Induced pluripotent stem cells (iPSCs), as adult cells with overexpression of pluripotency factors such as OCT4, NANOG, SOX2, c-Myc, KLF44, and more, can be highly similar to ESCs, with self-renewal properties, great differentiation potential, but might show genomic unstability. MSCs are multipotent, self-renewal, with easy accessibility and culturally expandable in vitro with exceptional genomic stability and few ethical issues, marking its importance in cell therapy, regenerative medicine and tissue repairment. #stemcell #Regenerativemedicine #MSCs

Before ASYMMETREX® was differentially counting tissue stem cells, we were differentially expanding them. Check out our innovative expansion technologies for licensing today. https://icont.ac/50TKm https://icont.ac/50TKn

𝗔 𝗰𝗵𝗮𝗻𝗴𝗲 𝗼𝗳 𝗵𝗲𝗮𝗿𝘁: 𝗳𝗿𝗼𝗺 𝘀𝘁𝗲𝗺 𝗰𝗲𝗹𝗹𝘀 𝘁𝗼 𝗯𝗲𝗮𝘁𝗶𝗻𝗴 𝗵𝗲𝗮𝗿𝘁 𝗰𝗲𝗹𝗹𝘀 💓 Even after almost a decade of working with induced pluripotent stem cells, every time I see cardiomyocytes spontaneously contracting in the lab I get as excited as the first time. These beating cells are a powerful reminder that ‘heart’ work does pay off! This video shows cardiomyocytes from my most recent differentiation, which then I used to create cardiac organoids for drug discovery experiments. #iPSC #Cardiomyocytes #RegenerativeMedicine

Just published! This work demonstrates the feasibility of producing stem cell derived extracellular vesicles in scalable bioreactors under clinically relevant serum-free, physioxic conditions, for stimulating vessel formation in brain endothelial cells - relevant to treatments for cerebral ishemia due to stroke, TBI https://lnkd.in/gEnsEJ7e

Sometimes the optimal cell therapy requires a mixture of cell types. In a new study (https://hubs.li/Q02yV5mY0) from the Catholic University of Korea, a rat model of spinal cord injury showed that combination of human motor neuron progenitor cells (iMAP) and human mesenchymal stem cells (MSCs) yielded better structural and behavioral improvements compared to either cell type alone. The iMNP cells were generated from iPSCs using a cocktail of Stemgent small molecules. Find out how REPROCELL can help you with your multicell type cell models: https://hubs.li/Q02yVggx0

Preserving cells is critical to research workflows. Our selection of cryo media covers T cells, MSCs, and stem cells to effectively maximize post-thaw viability and expansion to yield desired cell phenotypes. https://bit.ly/3Vl3TlZ

Who can afford to compromise on safety? During the culture of induced pluripotent stem cells (iPSCs), methodologies for the characterization and monitoring of key phenotypic markers, are crucial to ensure the preservation of pluripotency and homogeneity during growth. With cell therapy products, multiple safety issues, call for multiple solutions. This eBook provides a collection of data and methods for culture, optimization, and characterization of iPSCs, using cytometry as an analysis tool. Find out more: https://ow.ly/OkJF50SPPs4 #cellculture #livecellanalysis #highthroughputscreening #HTS #iPSCs #cytometry

This study provides some new insights into the molecular mechanism underlying age-related adipose stem cell (ASC) dysfunction, highlighting DUXAP10 and miR-214-3p as potential rejuvenating factors for aged stem cells. The finding is interesting and introduces potential novelty in the context of wound repair ability of ASCs. https://lnkd.in/eFpGHhz5

Preserving cells is critical to research workflows. Our selection of cryo media covers T cells, MSCs, and stem cells to effectively maximize post-thaw viability and expansion to yield desired cell phenotypes.