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Head Asia - Drug Delivery & Excipients

Cyclodextrins a "super molecules" Cyclodextrins are cyclic oligosaccharides composed of glucose units linked by α-1,4-glycosidic bonds. Their structure forms a toroidal or doughnut-shaped molecule with: Hydrophobic interior: This allows them to encapsulate non-polar molecules. Hydrophilic exterior: This makes them soluble in water. The most common types are: α-Cyclodextrin: Six glucose units. β-Cyclodextrin: Seven glucose units. γ-Cyclodextrin: Eight glucose units. Why It's a "Super Molecule" Encapsulation Capability: Cyclodextrins can form inclusion complexes by trapping guest molecules in their hydrophobic cavity. This property is used for stabilizing, solubilizing, and protecting various compounds. Environmental Friendliness: They are biodegradable, non-toxic, and derived from starch, making them an eco-friendly option in various industries. Versatility in Applications: Pharmaceuticals: Enhance drug solubility, stability, and bioavailability. Food Industry: Mask unpleasant tastes or odors and stabilize flavors. Cosmetics: Stabilize active ingredients and improve delivery. Environmental Science: Remove organic pollutants from water through encapsulation. Chemical Modifications: Cyclodextrins can be chemically modified (e.g., methylation, hydroxypropylation) to tailor their properties for specific applications. Self-Assembly: Cyclodextrins can act as building blocks for supramolecular assemblies, enabling the creation of nanomaterials, sensors, and drug delivery systems. Scientific and Industrial Impact Cyclodextrins exemplify the principles of supramolecular chemistry, where molecular recognition and host-guest interactions are key. Their use has revolutionized several fields, demonstrating the power of molecular engineering. If you'd like to explore specific applications or dive deeper into their chemistry, contact to CarboHyde

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Konstantin Lebedinskiy, PhD

Just finished my PhD and currently looking for new career opportunities.

1w

If we consider the price-performance ratio they certainly are

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