We have delved into the beautiful world of natural products🌿🌳 Past, present, and future!
Postdoc Carolina Cano Prieto, Postdoc Agustina Undabarrena, Postdoc Ana Calheiro de Carvalho, Professor Jay Keasling and Senior researcher Pablo Cruz-Morales from The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain), have created a comprehensive overview of the fascinating world of natural products, which have been indispensable as medicine and food throughout human history.👏
The overview and its insights have recently been published in the journal Annual Reviews of Biochemistry. Highlights from the paper include:
🔍 Historical overview: We provide a brief historical perspective on natural products, their classification, biosynthetic origins, and the microbiological and genetic methods used for their discovery.
🧬 Technological revolution: From classic genetics to genome-centric discovery, we describe the transformative technologies that have revolutionized the field over the past two decades.
🚀 Postgenomic era: Highlighting the most recent advancements, we discuss how genome mining and high-throughput analytical methods are enabling the parallel discovery of genes and molecules at an unprecedented pace.
🔮 Future challenges and innovations: We explore the new challenges faced by the field of natural products and the promising future of systematic heterologous expression and strain-independent discovery, poised to deliver more molecules in vials than ever before.
We are very proud of our team's contribution 👏 👏 👏
Enjoy the article in Annual Rewiews of Biochemistry here: https://lnkd.in/d2CCcjHJ
#Biotechnology #Biochemistry #Engineering #Research #Innovation
Novo Nordisk Foundation DTU - Technical University of Denmark