Market Access Today’s Post

Rethinking DALYs: Addressing the Methodological Limitations of a Widely Used Metric Proud to share our latest scientific publication, where we critically examine the methodological limitations of Disability-Adjusted Life Years (DALYs), one of the most prevalent metrics in public health and health economics with the QALY. While DALYs have been instrumental in shaping our understanding of the global burden of disease, our research sheds light on key challenges in their application. These include issues related to data consistency, assumptions about disability weights, and potential biases that can influence policy priorities. Our findings call for a more prudent approach to rank disease burden—one that considers alternative metrics to ensure equitable and effective resource allocation. This publication contributes to the ongoing dialogue on public health priorities about improving the tools we use to measure and address health challenges worldwide. As the field evolves, it's critical that we continuously refine our methods to better serve populations globally. https://lnkd.in/dbwXivQV I’d love to hear your thoughts: How can we improve the tools we rely on in public health to ensure more accurate and fair decision-making?  

Join me and our team next week at #ISPORAnnual to dive into the results of our studies and the latest #HEOR evidence that can help shaping healthcare decision making. Learn more below! #Takeda #TakedaOncology #mCRC #CML #ALL

Shocking! Data from the UK Clinical Practice Research Datalink GOLD (CPRD GOLD) show that: - 70.6% of young men and women, aged 16 to 39 years, living in the UK, had at least one chronic disease, - 42% of White men and women, aged 16 to 39 years, suffered from early onset of multimorbidity defined as the coexistence of 2 or more chronic diseases - 59% of South Asian and 56% of Black men and women (aged between 16 and 39 years old) had early onset of multimorbidity Compared to healthier individuals, those with multimorbidity expeinced 5 times the rate of hospitalisation and between a 6- to 12-fold higher odds of mortality. They also lost an average of 10.6 years of life after becoming multimorbid. https://lnkd.in/gMtsVpzH This is a disaster due to unhealthy lifestyle and environment. These trends not only escalate healthcare costs but also strain the sustainability of existing public healthcare systems, and show that simply increasing spending is not a viable solution. It is imperative to lead a cultural revolution reorienting our priorities from managing ‘chronic diseases’ to promoting ‘chronic health’. This entails not only changing individual behaviours but also establishing social and economic health models that prioritize prevention over treatment, with the aim of fostering optimal health throughout life, beginning even before conception. https://lnkd.in/gUKziu7k Integrating health literacy as soon as possible into education is key because it shapes health and well-being across people’s lives. despite the wealth of mechanistic knowledge linking nutrition, exercise, sleep, and cognitive and emotional training and health, these topics receive little or no attention in primary, secondary, and tertiary education, including medical schools. Schools and universities should not be a loose collocation of specialized academic silos but transformative engines that provide not only the expertise needed to have successful careers but also knowledge and practical skills on the mechanisms and interventions linking diet and other lifestyles to human and planetary health. https://lnkd.in/gw5FMiJ

🔍 Addressing the Gender Gap in Chronic Health Conditions Women are disproportionately affected by chronic illnesses like Alzheimer’s, depression, and osteoporosis, alongside female-specific conditions such as endometriosis and pelvic floor disorders. Despite living longer on average, women often endure a diminished quality of life due to these chronic conditions. The lack of research into both biological and social factors contributes to misdiagnoses and inappropriate treatments, leading to poorer health outcomes and substantial societal costs. It's time to bridge this research gap and ensure that women's health receives the attention it deserves. By prioritizing gender-specific research, we can achieve better health outcomes and move closer to health equity! #WomensHealth #HealthEquity #ChronicConditions #Research #GenderEquality #femtech #femtechua #femtechukraine

To advance the study of health equity in patient-centered outcomes research and the associated data infrastructure needs, the Assistant Secretary for Planning and Evaluation (ASPE) with the RAND Corporation are sponsoring a scientific symposium and accompanying special issue in the journal Medical Care focused on research findings that advance the understanding of the role of health equity in comparative effectiveness research and patient-centered outcomes research, including how social services may support health outcomes either in conjunction with health care services or independently. Abstracts of 500 words or less are due July 1. https://lnkd.in/ed-S7yk7

Significant gaps in what is known about chronic conditions that are specific to women hinder diagnosis, treatment and prevention, a new report shows. https://lnkd.in/etMeRSdc The National Academies of Sciences, Engineering, and Medicine Eve Higginbotham SM, MD, ML National Academy of Medicine #health #womenshealth #reproductivehealth #hormonalhealth #chronic #chronicillness #chronicdisease #wellbeing #research #study #gendergap

🚨🚨🚨New publication 🚨 🚨🚨 I am excited to announce our new research publication! This article is titled: Self-management needs, strategies and support for individuals with sickle cell disease in developing countries: a scoping review Living with sickle cell disease (SCD) comes with several challenges, especially in developing countries where access to healthcare is often limited. This review identifies the various self-management needs of SCD patients, including knowledge gaps, emotional challenges, physical constraints, and barriers to accessing care. In this study, we explored innovative strategies such as nutritional management and psychological coping techniques that help these individuals better manage their condition. Healthcare-led interventions proved especially impactful, with participants showing significant improvements in self-efficacy, knowledge, and overall well-being. This research brings us a step closer to understanding how we can better support SCD patients, and offers practical insights for healthcare providers and policymakers aiming to develop patient-centered care in resource-limited settings. I am particularly grateful to the faculty who always carry me along 🙏✊🙌. Mustapha Amoadu (PhD), DR. THEODORA DEDO AZU (FWACN, FFGCNM, RM, RGN, Ph.D.), Susanna Abraham PhD, christian boso PhD, Andrews Druye PhD, DORCAS FREMPOMAA AGYARE and all🥰🎉🙏 Check out the full article here: https://lnkd.in/euQtKSdq #SickleCellDisease #Healthcare #GlobalHealth #PatientSupport #SelfManagement #SCDCare #HealthcareAccess #ResearchAndInnovation #PublicHealthImpact

Excited to share that my article has been published in Taylor & Francis Group Expert review of pharmacoeconomics and outcomes research. You can find it here ⬇️ https://lnkd.in/eKVVA6zj #HealthEconomics #Multiplesclerosis

About time! CONSENSUS STUDY REPORT A New Vision for Women's Health Research: Transformative Change at the National Institutes of Health - link at bottom Women make up over half of the U.S. population, yet research on women’s health conditions, including those that are female specific such as fibroids, more common among women such as anxiety, or affect women differently such cardiovascular disease, is severely lacking. Medical advances for women have lagged, in part due to a lack of understanding of basic sex-based differences in physiology. To address this, the National Institutes of Health’s (NIH) Office of Research in Women’s Health tasked the National Academies with convening a committee of experts to assess the state of women’s health research at NIH, identify critical knowledge gaps, assess the level of funding for women’s health research, and more. The resulting report outlines specific recommendations for NIH women’s health research priorities; training and education efforts to build, support, and maintain a robust women’s health research workforce; improving internal structures, systems and processes; soliciting, reviewing, and supporting women’s health research; and ensuring appropriate levels of funding. https://lnkd.in/eHVaJQEN

Two years ago, the Mayo Clinic published a peer-reviewed study examining the impact of social determinants on hypertension control, emphasizing the racial disparities between Black and White patients.  The patients in the study were all enrolled in Ochsner Digital Medicine. It revealed that factors such as financial stress, health literacy, and patient activation significantly influenced hypertension outcomes. The data showed that, out of a cohort of 3,305, patients without these barriers had a 73% control rate at one year. However, the presence of even one barrier dropped control rates to 60%, and with two or more barriers, it fell to 55%. Addressing these barriers is key to improving outcomes—especially in populations more vulnerable to these challenges.  The study concluded that Ochsner Digital Medicine helps break down these barriers over time, reducing the disparity in blood pressure control outcomes. Our remote patient management program combines medication management from licensed clinicians, digital tools, and professional health coaching to achieve better results. Interested in diving deeper into the study? Read the peer-reviewed article here: https://lnkd.in/e8YxwYe8