a4cell’s Post

🔬 𝐑𝐞𝐯𝐨𝐥𝐮𝐭𝐢𝐨𝐧𝐢𝐳𝐢𝐧𝐠 𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐲: 𝐍𝐚𝐯𝐢𝐠𝐚𝐭𝐢𝐧𝐠 𝐭𝐡𝐞 𝐋𝐢𝐯𝐞 𝐂𝐞𝐥𝐥 𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐚𝐧𝐝 𝐀𝐧𝐚𝐥𝐲𝐬𝐢𝐬 𝐒𝐲𝐬𝐭𝐞𝐦 𝐌𝐚𝐫𝐤𝐞𝐭! 🌐🚀 𝐂𝐥𝐢𝐜𝐤 𝐇𝐞𝐫𝐞, 𝐓𝐨 𝐆𝐞𝐭 𝐅𝐫𝐞𝐞 𝐒𝐚𝐦𝐩𝐥𝐞 𝐑𝐞𝐩𝐨𝐫𝐭 https://lnkd.in/gibXYs_9 🌟 Key Highlights: Dynamic Cellular Exploration: Live Cell Imaging and Analysis Systems enable researchers to unlock the secrets of cellular dynamics in real-time, fostering breakthroughs in diverse scientific disciplines. Multidimensional Insights: From cancer research to drug discovery, these systems provide multidimensional insights, allowing scientists to observe, quantify, and analyze cellular behavior with unprecedented precision. Real-Time Cellular Monitoring: Advancements in real-time monitoring empower scientists to witness cellular processes as they unfold, offering invaluable information for understanding diseases and developing therapeutics. 💡 Market Dynamics: Global Scientific Impact: The market's influence spans the globe, driving advancements in academic research, pharmaceutical development, and biotechnological innovations. Interdisciplinary Applications: Live Cell Imaging and Analysis Systems find applications across disciplines, from microbiology and immunology to neuroscience, reflecting their versatility and impact. #Company Sartorius Agilent Technologies Molecular Devices Etaluma, Inc. Leica Biosystems PerkinElmer Axion BioSystems CytoSMART Technologies Celloger Nano (Curiosis) Thermo Fisher Scientific #Type • Primary Cell • Cell Line #Application • Cell Biology • Drug Screening • Tumor Research • Others #LiveCellImaging #ScientificDiscovery #Biotechnology #CellularExploration #InnovationInScience #LinkedInPost

𝐒𝐢𝐫𝐢𝐮𝐬𝐗𝐓 𝐚𝐧𝐝 𝐜𝐨𝐥𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐬 𝐩𝐫𝐞𝐬𝐞𝐧𝐭 𝐭𝐡𝐞 𝐒𝐗𝐓-100 𝐒𝐨𝐟𝐭 𝐗-𝐫𝐚𝐲 𝐌𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞 𝐚𝐭 𝐄𝐌𝐂2024 - 𝐛𝐫𝐢𝐧𝐠𝐢𝐧𝐠 𝐭𝐡𝐞 𝐩𝐨𝐰𝐞𝐫 𝐨𝐟 𝐭𝐡𝐞 𝐬𝐲𝐧𝐜𝐡𝐫𝐨𝐭𝐫𝐨𝐧 𝐭𝐨 𝐭𝐡𝐞 𝐥𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲!🔬 The image below shows Dr. Johannes Groen, Institut Pasteur, Paris, presenting results of trials to integrate Soft X-ray Tomography (SXT) into correlative imaging workflows. The goal is to demonstrate that faster and more accurate targeting of regions of interest in a cell, using SXT, leads to more efficient and higher-throughput imaging workflows and, ultimately, accelerates the understanding of disease mechanisms and the development of new vaccines and therapeutics! 💻To learn more about Soft X-ray Tomography visit https://bit.ly/3S5LoAa ✉or email us at: info@siriusxt.com #emc2024 #Innovation #SXT #Laboratory #Synchrotron #Science #Research #Microscopy #Microscope #Copenhagen #Denmark #EU #STEM #Networking #Conference #Event #SiriusXT #SXT #Biotech #Biology #Imaging #Presentation #Paris #Collaboration #Vaccines

𝗘𝗻𝗵𝗮𝗻𝗰𝗶𝗻𝗴 𝗵𝗶𝗣𝗦𝗖-𝗖𝗠 𝗺𝗮𝘁𝘂𝗿𝗮𝘁𝗶𝗼𝗻 𝘄𝗶𝘁𝗵 𝗧𝟯 𝗮𝗻𝗱 𝗗𝗲𝘅: 𝗔 𝗺𝘂𝗹𝘁𝗶𝗽𝗹𝗲𝘅 𝗮𝗽𝗽𝗿𝗼𝗮𝗰𝗵 🫀✨ Are you working with hiPSC-derived cardiomyocytes (hiPSC-CMs) and looking to improve their maturation for applications in disease modeling, drug discovery, or cell therapy? We've got something exciting to share with you! In collaboration with Bayer, Fraunhofer IBMT, and Hamamatsu Photonics France, we've developed an application note that dives into how triiodothyronine (T3) and dexamethasone (Dex) can enhance the structural and functional maturation of hiPSC-CMs. Our study combines impedance/EFP and calcium imaging to track calcium transients and electrical activity in the same cells. The results are promising, T3 and Dex not only modulate the electrical activity but also improve calcium handling, crucial for the maturation of these cells. We also explored how the NSP-96 transparent plate can be used for multiple assays, allowing you to measure electrical activity, contractility, and calcium transients from the same cell population using the CardioExcyte 96 and FDSS/μCELL. This means more data from fewer cells and reduced variability. Curious to learn more? Check out the full application note here: https://ow.ly/bwVS50T1NC4 #Cardiomyocytes #hiPSC #StemCells #DrugDiscovery #CellAnalytics #CardioExcyte96

🌐 Driving Synergies with Emerging Technologies in 3D Cell Culture Research 🌐 The use of 3D cell cultures is revolutionizing in vitro research, offering more relevant and predictive data that closely resembles in vivo conditions. Yet, to truly unlock the potential of these advanced models, creating synergies between emerging technologies is essential. Integrating these innovations not only facilitates their adoption but also maximizes their benefits for users, driving research efficiency, faster decision-making, and cost-effective outcomes. At ARRAYS FOR CELL NANODEVICES, SL - A4CELL, we offer #SPAchip technology to complement 3D cell culture models, empowering researchers to achieve more impactful results. By combining these advancements, we pave the way for optimized assays and transformative discoveries. Discover how #SPAchip can elevate your research through powerful technological synergies!

🌐 The Rise of 3D Cell Cultures in In Vitro Research 🌐 3D cell cultures are transforming in vitro studies, offering more physiologically relevant data that mirrors in vivo conditions. As research grows more complex, combining emerging technologies is essential to boost efficiency, speed up decision-making, and lower experimental costs. Our #SPAchip technology enhances 3D cell culture models, providing a powerful foundation to optimize your assays and elevate your research outcomes. Discover the future of in vitro studies with A4cell’s innovative solutions! #SPAchip #technology #drugdiscovery #innovation #biotech #3Dmodels #spheroids

I can only recommend this upcoming session. and even though I am more in my proteomics bubble, its fantastic to see the LCMS field progress in Metabolomics :)

Q&A on Cannabinoid Translational Science with Uwe Grether! Scroll down to discover the questions and in-depth responses! #cannabinoidtranslationalscience #uwegrether Registration: https://lnkd.in/d8ZxwYD7

PD-value is coming to AcoP2024 in Phoenix, Arizona. Did you know we also perform systems biology and QSP modeling? With systems approaches, you can leverage available knowledge on how biology reacts to your drug. Or even drug concept. In drug development, teams use systems modeling to select patient populations and clinical trial inclusion criteria. Systems approaches are also used to evaluate drug targets and modalities. And of course we also perform PK-PD modeling, or QSP modeling which is in-between the two. We support teams with in vitro and in vivo modeling of cell interactions, with or without linking to PBPK models. An example in high demand is in vitro modeling of bi-specific T-cell engagers. The photo shows Kathrin Thedieck, professor in systems biology, with whom we collaborate in multiple projects, during the PD-value lustrum symposium. Curious how we deliver value to our clients? Please stop by our booth, or leave a comment and we will contact you.

Q&A on Cannabinoid Translational Science with Laura Heitman! Scroll down to discover the questions and in-depth responses! #cannabinoidtranslationalscience #LauraHeitman Registration: https://lnkd.in/d8ZxwYD7

According to this impactful piece, the field of targeted protein degradation (TPD) is burgeoning, and shows promising applications in neuroscience and clinical development. It states "TPD offers innovative strategies for modulating protein levels, presenting a paradigm shift in small-molecule drug discovery and therapeutic interventions." https://lnkd.in/g9wFWn24 We agree. Proteomics will become an essential part of TPD R&D. However challenges lie ahead: navigation fragile workflows, limited proteomics expertise, overwhelming volumes of data, and stretched resources. And that's why it's a no-brainer to be debuting as sponsoring exhibitors at the TPD + Induced Proximity Summit in Boston. Kicking off on October 28th. We’re excited to join the conversation and connect with innovators driving the field forward. Stop by booth #12 to meet Andrew Webb, Paula Burton, Giuseppe Infusini, and Mark Condina, to chat about common challenges in TPD-based proteomics. In our 15-minute live sessions at the Booth, we'll be showcasing how Mass Dynamics streamlines complex workflows, empowers teams to do more with less, and accelerates data-driven decisions. We look forward to seeing you there! https://lnkd.in/d3eQYYE #tpd #targetedproteindegradation #proteindegradation #drugdiscovery #tpd2024 #proteomics #masspec #teamMassSpec #massspectrometry #lifescience #hansonwade #biotech #biopharma #proteindegraders #undruggable Hanson Wade Group Charlotte Hodgson Jacob Roberts-Kendall