Tzafon Medical Center’s Post

I am excited and thrilled to share my experience in the 8th IUBMB congress whose theme was Enhancing interdisciplinary partnership in Biochemistry and Biotechnology across Africa. It was such an insightful conference,no one mentions how engaging it can get when you attend a conference and the key note speakers are professors and doctors My key take homes were: - [x] How climate change is contributing to Antimicrobial resistance by promoting the suitable environment for the new strains to thrive and promoting epidemic outbreaks which result in extensive use of antibiotics - [x] The role of the pharmaceutical industry in manufacturing drugs that can be taken for short periods instead of very extensive periods - [x] How environment pollution is also a key contributor to AMR Please share your thoughts on key promoters of AMR - [ ] Another key take home was the use of AI intelligence in revolutionizing the healthcare system I want to pass my special regards to Dr.Clarence Mang’era who enabled us to attend the congress and the Kenya Monetary School of Studies for hosting the congress.

‘Forever chemicals’ like perfluorooctanoic acid (PFOA) have been linked to a host of health issues —from cancer to impaired fetal growth. 💡 Researchers at the A*STAR Singapore Institute of Food and Biotechnology Innovation (SIFBI), A*STAR Skin Research Labs (A*SRL) and the National University of Singapore pioneered a computational model that simulates how the human body handles PFOA. As a strongly charged molecule, PFOA cannot readily enter or exit human cells, often relying on transporters to get the job done. “All the known transporters of PFOA were responsible for pumping PFOA into kidney cells, but none were documented to pump it out,” explained James Chan, a Junior Principal Investigator at SIFBI and A*SRL. “We therefore hypothesised that there must be an efflux transporter that acts as a release valve to pump PFOA out of the kidney cells and back into the blood.” Get a behind-the-scenes look at their study in the article linked below ⬇️ --- #scicomm #science #technology #STEM #research #innovation #ASTAR #HHP #ASRL #SIFBI #toxicokinetics #health #foreverchemicals #collaboration #Singapore

We are hosting an interesting webinar with global experts on #biomedicalresearch, organoids and organ-on-chip as the modern frontier of #drugdevelopment. Interested people are invited to register. Registration link and more deets below. https://lnkd.in/gVzu9swH #replacinganimaltesting #humanbaseddrugdevelopment

🚨 New Publication on #E4 in collaboration with Fuji Pharma Co. Ltd., Estetra, QUALIblood and two leading medical centers in #Japan — Hamamatsu University School of Medicine and Tottori University Faculty of Medicine! We are excited to share our latest research on the impact of #Estetrol combined with #Drospirenone on blood coagulation and fibrinolysis in patients with endometriosis. This study provides valuable insights into the safety profile of E4-based treatments for managing #endometriosis. This multicenter study demonstrated that the combination of E4 and DRSP had a significantly lesser impact on coagulation and fibrinolysis compared to Ethinyl Estradiol-based treatments, highlighting a promising approach for safer therapeutic options. Many thanks to our partners at Fuji Pharma Co. Ltd., Estetra, QUALIblood and the teams at Hamamatsu University School of Medicine and Tottori University for their exceptional collaboration. Together, we aim to advance women's health and bring innovative treatments to patients worldwide. 🔗 Read the full study below ⬇️ Unité de Recherche en Pharmacologie Clinique et Toxicologie (URPC) - Namur Research Institute for Life Sciences (NARILIS) - Université de Namur #Research #Innovation #Endometriosis #WomensHealth #E4

𝗗𝗮𝘆 𝟰𝟬, 𝗣𝗮𝘀𝘀𝗮𝗴𝗲 𝟯: 𝗪𝗶𝘁𝗻𝗲𝘀𝘀𝗶𝗻𝗴 𝘁𝗵𝗲 𝗚𝗿𝗼𝘄𝘁𝗵 𝗼𝗳 𝗧𝗶𝗻𝘆 𝗠𝗶𝗿𝗮𝗰𝗹𝗲𝘀 🌱 It's been a dedication and hard work journey, but the organoids growing at King Faisal Specialist Hospital and Research Center labs are thriving! Here's a closer look into the world of organoid cultivation: • Patience is Key: Growing organoids requires care, precise protocols, and patience. ⏳ • Learning from Mistakes: Not every experiment goes as planned. We've faced challenges, but each setback is a valuable learning opportunity, pushing us closer to success. 💡    • The Future is Bright: These tiny organ-like structures hold potential for disease modeling, drug testing, and understanding disease development.      We're excited to see what the future holds! 🚀 #organoids #medicalresearch #stemcells #biotechnology #researchlife #science #futureofmedicine # #Bioengineering #KFSHRC

Few researchers and organisations have the expertise, skills, and infrastructure to tackle #AMR and discover new #antibiotics. Long-term funding for #antibiotic development partnerships will help attract young scientists to the field and keep companies in anti-infective drug development. To secure a sustainable future for efforts of this scale, we call on government leaders, the private sector and other stakeholders to invest in the development of antibiotics and AMR research.   The AMR Accelerator is an Innovative Health Initiative (IHI) programme integrating nine projects with the shared goal of progressing the development of new antibiotics and building #antimicrobial resistance research capability. Five years in, we reflect on the programme’s value, results and key challenge: ensuring the sustainability of our assets, infrastructures and expertise. Read more in our article: https://lnkd.in/eqGbRqmg Explore our results: https://lnkd.in/ebSUbVhB

#𝐂𝐄𝐃𝐇𝐔𝐂𝐏 𝐏𝐚𝐩𝐞𝐫 𝐌𝐨𝐦𝐞𝐧𝐭? 🔎 📌Our researchers Patrícia Batista and Patrícia Oliveira-Silva co-authored the article “Fucoidans: exploring its neuroprotective mechanisms and therapeutic applications in brain disorders”, in partnership with the CBQF - Centre for Biotechnology and Fine Chemistry, published in the 'Trends in Food Science & Technology'. The team's findings are a game-changer in both the food and pharmaceutical industries, revealing Fucoidan's diverse health benefits. 🔎 Key Findings: - Fucoidan boasts potent antioxidant and anti-inflammatory properties - It may positively influence our gut microbiota, proving its prebiotic potential. - Preliminary in vitro and in vivo studies show its effectiveness in neuroprotection. Read more 👉 https://rb.gy/o1iacs #UniversidadeCatólicaPortuguesa #UCP #CatólicaPorto #EnsinoSuperior #universidade #faculdade #FaculdadeEducaçãoPsicologia #FEPUCP #CEDHUCP #scientificpaper #brain #Fucoidan #neuroprotectivemechanisms #healthbenefits #CBQF Faculdade de Educação e Psicologia – Universidade Católica Portuguesa (Porto) Universidade Católica Portuguesa - Centro Regional do Porto Universidade Católica Portuguesa

Hi #connections, "Excited to share my latest publication on [EVALUATION OF THE HEPATOPROTECTIVE ACTIVITY OF FORMULATION CONTAINING ANDROGRAPHOLIDE ON HEPATOTOXICITY INDUCED ALBINO WISTAR RAT], This study delves into [hepatpprotective activity] and offers valuable insights for [relevant industry/field]. I'd love to hear your thoughts and discuss further! #Research #Publication #Science", Here is the link: https://lnkd.in/gFNRpi3q

⏳ The clock is running: less than ONE month to go for the next evaluation! ENABLE-2 INCUBATOR - HIT IDENTIFICATION AND VALIDATION Compound eligibility criteria: • Novel compounds with some documented whole cell antibacterial activity against any species or strain (including efflux-deficient or hyperpermeable strains), with a MIC of at least 32 µg/mL, or • Novel compounds with only documented bacterial target activity. • Potential for development as direct-acting antibiotics for systemic use. • Not previously reported to have antibacterial activity. • Antimicrobial peptides with only membrane perturbation activity are not eligible. • Novel natural products are eligible Who can apply? Researchers at publicly funded universities and research institutes in Europe (including non-EU countries such as UK, Norway, Switzerland etc.) are eligible. The call is open continuously. Expressions of Interest submitted by 30 August 2024 will be evaluated by end of September 2024. More info & Expression of Interest ➡ https://lnkd.in/d27wU4KZ #antimicrobialresistance #antibioticresistance #antibiotics #amr

More on the #ISBER2025 Scientific Task Force.