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Landiolol is an ultra-short-acting, selective β1-adrenergic receptor blocker that was origi- nally approved in Japan for the treatment of intraoperative tachyarrhythmias. It has gained attention for its use in the management of tachyarrhythmias and perioperative tachycardia, especially atrial fib- rillation for both cardiac and non-cardiac surgeries. It can be the ideal agent for heart rate control due to its high β1-selectivity, potent negative chronotropic effect, a limited negative inotropic potential, and an ultrashort elimination half-life (around 4 min); moreover, it may have a potential therapeutic effects for sepsis and pediatric patients. Landiolol seems to be superior to other short-acting and selective beta-blockers such as esmolol.

https://lnkd.in/gCtaaytb Article title: Should We Screen Patients with Unprovoked Venous Thromboembolism for Hyperthyroidism? Report of Several Paradigmatic Clinical Cases from the RIETE Registry   Author(s): Pierpaolo Di Micco*; Gualberto Gussoni; Fernando Uresandi; Agustina Rivas; Raquel López-Reyes; Lucia Mazzolai; Rita Duce; Andrei Braester; Pilar Llamas; Manuel Monreal   Journal: Archives of Hematology Case Reports and Reviews   Journal ISSN: 2640-7914 Abstract: Unprovoked venous thromboembolism (VTE) is defined as a VTE appearing in the absence of the common risk factors including cancer, surgery, hypomobility, oestrogen use or pregnancy. Around 40% of VTE patients have unprovoked VTE in real life. However, a number of additional clinical conditions may be associated to ahypercoagulable state and induce VTE, though they are less often considered in clinical practice such as the abnormalities of the thyroid function. Here we report three relevant case-reports that we found in the RIETE registry in which overt hyperthyroidism is the only apparent cause of haemodynamic unstable acute pulmonary embolism (PE). #Anemia #AcuteMyeloidLeukemia #LymphAngiogenesis #HematologicalMalignancies #BloodTransfusion #SerumProteinElectrophoresis #HematopoieticStemCellTransplantation #PhotoAcoustics #LymphNodeBiopsy #BCellLymphoma #InvivoFlowCytometry #ChainsofHemoglobin #Lymphoma #HodgkinsLymphoma #Coagulation #Thalassemia #NonHodgkinsDisease #MultipleMyeloma #StemCellsAndHematopoiesis #LeukocytesAndPlatelets #RedCellBiology #HematologicNeoplasia #Immunobiology #BloodAndMarrowTransplantation #TransfusionMedicine #VascularBiology #Hemobiology #Peertechz #PeertechzPublications #OpenAccess #ScientificJournals #PeerReviewedJournals #OpenAccessPublishers

🌸 Exploring Pediatric Ovarian Masses: Understanding the Spectrum 🌸 In pediatric patients, ovarian masses present a diverse range of conditions, encompassing both benign and malignant tumors. These masses, specifically termed ovarian tumors, signify abnormal growths in the ovaries, varying in their nature from benign to malignant. 🟣 Benign Lesions: Common benign masses in children include simple or epithelial cysts, teratomas, and granulosa cell tumors. While typically non-cancerous, they necessitate proper evaluation and may be managed conservatively with surgical approaches to preserve function. 🟣 Malignant Tumors: Though less frequent, malignant ovarian tumors in children pose greater concern due to their potential for spreading to other organs. They encompass germ cell tumors, epithelial cell tumors, stromal cell tumors, or metastatic lesions, requiring aggressive treatment modalities like surgery, chemotherapy, or radiation. 🔍 Diagnosis: Accurate differentiation between benign and malignant masses is pivotal for determining appropriate management strategies. While ultrasound aids in initial identification, further evaluation through imaging studies and tumor markers is often indispensable. The intricate balance between diagnosis and treatment underscores the importance of a multidisciplinary approach in pediatric ovarian masses. Let's continue the conversation and share our insights on optimizing care for these young patients. #PediatricOvarianMasses #OvarianTumors #ChildhoodCancerAwareness #PediatricOncology

🌿 What is a Colectomy? 🌿 A Colectomy is a surgical procedure to remove all or part of your colon. It's typically done to treat or prevent conditions like colon cancer, inflammatory bowel disease, or diverticulitis. Surjen Healthcare provides expert, top-tier care for patients requiring this procedure. 👉 Learn more about Colectomy and how we can help you with expert surgical care. 🔗 Learn more: https://lnkd.in/dNxdvf8h #SurjenHealthcare #Colectomy #ColonSurgery #SurgicalCare #GastrointestinalHealth #DigestiveHealth #ColonHealth #ColorectalSurgery #HealthcareExcellence #SurjenCares #PatientCare #SurgeryInNigeria #HealthAndWellness #ColonCancerPrevention #HealthcareServices #MedicalSurgery #SurgicalProcedure #ExpertSurgeons #SurgicalExcellence #Gastroenterology #QualityCare

Today honors World Gynecologic Oncology Day – a time dedicated to raising awareness about gynecologic cancers and the importance of early detection, medical advancements in treatment, and support for those affected. Gynecologic cancers, including ovarian, cervical, uterine, and others, impact countless women across the globe each year. Given that many gynecologic surgeries, such as laparoscopic hysterectomies or myomectomies, are transitioning to outpatient procedures, identifying innovative pain management options to enhance the recovery process is crucial to ensure that women are returning home with minimal pain. #NonOpioid options can provide a safe and effective option for women while eliminating the risks associated with opioids, which is especially important considering that women are 40% more likely than men to become persistent opioid users when prescribed narcotics after surgery.

The Hepatic Series: Liver Transplantation Liver transplantation is a life-saving procedure for those with end-stage liver disease, offering a second chance at life. While the journey can be challenging, it’s a testament to the strength and resilience of the human body. Understanding the process, recovery, and long-term care is essential for those facing this path. Let’s spread awareness about the importance of organ donation and support for transplant patients. Together, we can make a difference. 🌱💚 [Liver transplant, organ donation, end-stage liver disease, transplant recovery, liver health, life-saving surgery, resilience, patient support, post-transplant care, liver care.] #LiverTransplant #OrganDonation #TransplantAwareness #LiverHealth #TransplantJourney #LifeAfterTransplant #LiverCare #LiverDisease #EndStageLiverDisease #LiverSupport #TransplantRecovery #HealthyLiver #LiverWellness #LiverLife #TransplantSuccess #LiverFunction #HealthAwareness #SupportLiverHealth #TransplantCommunity #LiverTreatment #DonateLife #LiverPrevention #LiverAwareness #HealthEducation #Transplantation

So a quick updated should we consider referring this lady to physiotherapy or not? L We should consider referring this patient to physiotherapy, as it could be a valuable management option, especially for improving muscle strength and spinal stability. However, it’s essential to ensure there are no red flags and that she is medically stable before proceeding. Gandhi et al. (n.d.) highlighted positive outcomes of physiotherapy in managing wedge compression fractures of the L1 vertebra. Moreover, Kato et al. (2022) identified abdominal muscle weakness as a significant risk factor for future osteoporotic vertebral fractures in middle-aged and older women. Resources https://lnkd.in/ecamXHfi. https://lnkd.in/enFv8Tkw

Depending on the type and stage of #sarcoma, chemotherapy may be given as the main treatment or as an adjuvant (addition) to surgery. However, when it comes to #Chemotherapy, there are so many unproven #myths that it can be very difficult to sort out the #facts from the #fiction. Today we will take a look at a few of the common misconceptions about Chemotherapy and the truth behind these #myths. Myth 1: Chemotherapy will make me sick. Fact: While that used to be the case, patients can now take medicines before chemotherapy to prevent side effects like #nausea and #vomiting. On average only one or two out of 150 patients experience nausea. And those who do usually only have it for a short period of time. Myth 2: I will lose all my hair. Fact: Not every chemotherapy drug causes #HairLoss and some only cause hair thinning. It depends on the type of #chemo you get as well as the combination of drugs. Most chemotherapy affects rapidly dividing cells in the body, like those in the hair follicle. But sometimes, patients can take targeted medicines that influence specific cells. With these drugs, the hair is rarely affected. For patients at risk of losing their hair, scalp cooling may help. During this innovative procedure, the patient is fitted with a special cold cap that diminishes blood flow to the scalp, theoretically reducing the amount of chemo that comes in contact with hair follicles. Your doctor can tell you if you would be a good candidate for scalp cooling. It is important to note, however, that the cap must be worn for hours at a time. Myth 3: My life will be drastically interrupted while I have chemo. Fact: Absolutely not. Many people go to work every single day. They may have a day or two when they are not feeling their greatest, but that could happen to anyone. Myth 4: I will not be able to have children after chemo. Fact: Every effort is made to spare a patient’s fertility. Men can bank and/or freeze their sperm. Women can freeze their eggs or take medications that suppress ovarian function during treatment. Many women go on after chemotherapy to have safe pregnancies and healthy children. For consultation with an #OrthopaedicOncologist, please call on ph 022 3547 5757 or click on the link https://buff.ly/3U7tfmT

A young man with cystic fibrosis (CF) underwent a groundbreaking heart transplant due to a rare CF complication, as detailed in a new report. Though CF typically affects the lungs and pancreas, this case highlights the potential for heart involvement. The transplant was performed at age 12 after heart failure, with challenges like lung infections managed post-surgery. With Trikafta treatment, the patient saw significant lung improvement by age 24, showing the impact of advanced care for rare CF complications. To read more: https://lnkd.in/g7usVVH2 #CysticFibrosis #HeartTransplant #CFResearch #Trikafta #CFA

Breast cancer awareness starts with understanding the symptoms and available treatments. Knowing what to look for can save lives. ✔️ Symptoms: • A lump or thickening in the breast or underarm. • Changes in the size, shape, or appearance of the breast. 🔄 • Redness, dimpling, or puckering of the breast skin. ‼️ • Unexplained nipple discharge or pain. Treatment Options: 🚒 • Surgery (lumpectomy or mastectomy). • Radiation therapy. • Chemotherapy. • Hormonal therapy. • Targeted therapy. Early detection is key. Don’t ignore the signs. Consult your healthcare provider for regular screenings. #BreastCancerAwareness #EarlyDetection #FightCancer #BreastHealth #CancerPrevention #StayInformed #hospital #doctor #coordinator #healthcare